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Systems Biology of Cancer: A Challenging Expedition for Clinical and Quantitative Biologists

Overview of attention for article published in Frontiers in Bioengineering and Biotechnology, August 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (56th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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3 X users
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1 Google+ user

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42 Mendeley
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Title
Systems Biology of Cancer: A Challenging Expedition for Clinical and Quantitative Biologists
Published in
Frontiers in Bioengineering and Biotechnology, August 2014
DOI 10.3389/fbioe.2014.00027
Pubmed ID
Authors

Ilya Korsunsky, Kathleen McGovern, Tom LaGatta, Loes Olde Loohuis, Terri Grosso-Applewhite, Nancy Griffeth, Bud Mishra

Abstract

A systems-biology approach to complex disease (such as cancer) is now complementing traditional experience-based approaches, which have typically been invasive and expensive. The rapid progress in biomedical knowledge is enabling the targeting of disease with therapies that are precise, proactive, preventive, and personalized. In this paper, we summarize and classify models of systems biology and model checking tools, which have been used to great success in computational biology and related fields. We demonstrate how these models and tools have been used to study some of the twelve biochemical pathways implicated in but not unique to pancreatic cancer, and conclude that the resulting mechanistic models will need to be further enhanced by various abstraction techniques to interpret phenomenological models of cancer progression.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 2%
Brazil 1 2%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 26%
Student > Ph. D. Student 9 21%
Professor 5 12%
Student > Master 5 12%
Professor > Associate Professor 4 10%
Other 4 10%
Unknown 4 10%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 24%
Agricultural and Biological Sciences 7 17%
Medicine and Dentistry 7 17%
Computer Science 3 7%
Chemical Engineering 2 5%
Other 7 17%
Unknown 6 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2014.
All research outputs
#7,445,297
of 22,760,687 outputs
Outputs from Frontiers in Bioengineering and Biotechnology
#1,267
of 6,524 outputs
Outputs of similar age
#75,280
of 235,512 outputs
Outputs of similar age from Frontiers in Bioengineering and Biotechnology
#6
of 14 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,524 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 80% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,512 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.