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Lifetime Distributions from Tracking Individual BC3H1 Cells Subjected to Yessotoxin

Overview of attention for article published in Frontiers in Bioengineering and Biotechnology, October 2015
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Title
Lifetime Distributions from Tracking Individual BC3H1 Cells Subjected to Yessotoxin
Published in
Frontiers in Bioengineering and Biotechnology, October 2015
DOI 10.3389/fbioe.2015.00166
Pubmed ID
Authors

Mónica Suárez Korsnes, Reinert Korsnes

Abstract

This work shows examples of lifetime distributions for individual BC3H1 cells after start of exposure to the marine toxin yessotoxin (YTX) in an experimental dish. The present tracking of many single cells from time-lapse microscopy data demonstrates the complexity in individual cell fate and which can be masked in aggregate properties. This contribution also demonstrates the general practicality of cell tracking. It can serve as a conceptually simple and non-intrusive method for high throughput early analysis of cytotoxic effects to assess early and late time points relevant for further analyzes or to assess for variability and sub-populations of interest. The present examples of lifetime distributions seem partly to reflect different cell death modalities. Differences between cell lifetime distributions derived from populations in different experimental dishes can potentially provide measures of inter-cellular influence. Such outcomes may help to understand tumor-cell resistance to drug therapy and to predict the probability of metastasis.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 2 40%
Student > Bachelor 1 20%
Researcher 1 20%
Unknown 1 20%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 1 20%
Biochemistry, Genetics and Molecular Biology 1 20%
Psychology 1 20%
Unknown 2 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2015.
All research outputs
#18,429,163
of 22,830,751 outputs
Outputs from Frontiers in Bioengineering and Biotechnology
#3,396
of 6,565 outputs
Outputs of similar age
#203,717
of 283,225 outputs
Outputs of similar age from Frontiers in Bioengineering and Biotechnology
#40
of 63 outputs
Altmetric has tracked 22,830,751 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,565 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 283,225 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.