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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Engineering of Metabolic Pathways by Artificial Enzyme Channels
|
|---|---|
| Published in |
Frontiers in Bioengineering and Biotechnology, October 2015
|
| DOI | 10.3389/fbioe.2015.00168 |
| Pubmed ID | |
| Authors |
Marlene Pröschel, Rainer Detsch, Aldo R. Boccaccini, Uwe Sonnewald |
| Abstract |
Application of industrial enzymes for production of valuable chemical compounds has greatly benefited from recent developments in Systems and Synthetic Biology. Both, in vivo and in vitro systems have been established, allowing conversion of simple into complex compounds. Metabolic engineering in living cells needs to be balanced which is achieved by controlling gene expression levels, translation, scaffolding, compartmentation, and flux control. In vitro applications are often hampered by limited protein stability/half-life and insufficient rates of substrate conversion. To improve stability and catalytic activity, proteins are post-translationally modified and arranged in artificial metabolic channels. Within the review article, we will first discuss the supramolecular organization of enzymes in living systems and second summarize current and future approaches to design artificial metabolic channels by additive manufacturing for the efficient production of desired products. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| Unknown | 3 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 206 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | <1% |
| United States | 2 | <1% |
| China | 1 | <1% |
| Unknown | 201 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 54 | 26% |
| Researcher | 29 | 14% |
| Student > Master | 23 | 11% |
| Student > Bachelor | 14 | 7% |
| Professor | 10 | 5% |
| Other | 41 | 20% |
| Unknown | 35 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 63 | 31% |
| Agricultural and Biological Sciences | 50 | 24% |
| Chemistry | 13 | 6% |
| Chemical Engineering | 9 | 4% |
| Engineering | 6 | 3% |
| Other | 22 | 11% |
| Unknown | 43 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2022.
All research outputs
#2,596,893
of 25,002,811 outputs
Outputs from Frontiers in Bioengineering and Biotechnology
#320
of 8,207 outputs
Outputs of similar age
#35,833
of 289,247 outputs
Outputs of similar age from Frontiers in Bioengineering and Biotechnology
#2
of 64 outputs
Altmetric has tracked 25,002,811 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,207 research outputs from this source. They receive a mean Attention Score of 3.5. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,247 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.