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Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma

Overview of attention for article published in Frontiers in Bioengineering and Biotechnology, December 2017
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  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

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130 Mendeley
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Title
Nanoparticles—Emerging Potential for Managing Leukemia and Lymphoma
Published in
Frontiers in Bioengineering and Biotechnology, December 2017
DOI 10.3389/fbioe.2017.00079
Pubmed ID
Authors

Raquel Vinhas, Rita Mendes, Alexandra R. Fernandes, Pedro V. Baptista

Abstract

Nanotechnology has become a powerful approach to improve the way we diagnose and treat cancer. In particular, nanoparticles (NPs) possess unique features for enhanced sensitivity and selectivity for earlier detection of circulating cancer biomarkers. In vivo, NPs enhance the therapeutic efficacy of anticancer agents when compared with conventional chemotherapy, improving vectorization and delivery, and helping to overcome drug resistance. Nanomedicine has been mostly focused on solid cancers due to take advantage from the enhanced permeability and retention (EPR) effect experienced by tissues in the close vicinity of tumors, which enhance nanomedicine's accumulation and, consequently, improve efficacy. Nanomedicines for leukemia and lymphoma, where EPR effect is not a factor, are addressed differently from solid tumors. Nevertheless, NPs have provided innovative approaches to simple and non-invasive methodologies for diagnosis and treatment in liquid tumors. In this review, we consider the state of the art on different types of nanoconstructs for the management of liquid tumors, from preclinical studies to clinical trials. We also discuss the advantages of nanoplatforms for theranostics and the central role played by NPs in this combined strategy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 130 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 26 20%
Student > Master 17 13%
Student > Bachelor 15 12%
Researcher 12 9%
Unspecified 6 5%
Other 19 15%
Unknown 35 27%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 17 13%
Biochemistry, Genetics and Molecular Biology 16 12%
Chemistry 10 8%
Medicine and Dentistry 10 8%
Agricultural and Biological Sciences 7 5%
Other 25 19%
Unknown 45 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2017.
All research outputs
#14,370,803
of 23,012,811 outputs
Outputs from Frontiers in Bioengineering and Biotechnology
#1,949
of 6,714 outputs
Outputs of similar age
#238,619
of 439,953 outputs
Outputs of similar age from Frontiers in Bioengineering and Biotechnology
#10
of 26 outputs
Altmetric has tracked 23,012,811 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,714 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 439,953 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.