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Adult stem cell and mesenchymal progenitor theories of aging

Overview of attention for article published in Frontiers in Cell and Developmental Biology, March 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (52nd percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

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4 X users
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2 Facebook pages

Citations

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38 Dimensions

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81 Mendeley
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Title
Adult stem cell and mesenchymal progenitor theories of aging
Published in
Frontiers in Cell and Developmental Biology, March 2014
DOI 10.3389/fcell.2014.00010
Pubmed ID
Authors

So-ichiro Fukada, Yuran Ma, Akiyoshi Uezumi

Abstract

Advances in medical science and technology allow people live longer lives, which results in age-related problems. Humans cannot avoid the various aged-related alterations of aging; in other words, humans cannot remain young at molecular and cellular levels. In 1956, Harman proposed the "free radical theory of aging" to explain the molecular mechanisms of aging. Telomere length, and accumulation of DNA or mitochondrial damage are also considered to be mechanisms of aging. On the other hand, stem cells are essential for maintaining tissue homeostasis by replacing parenchymal cells; therefore, the stem cell theory of aging is also used to explain the progress of aging. Importantly, the stem cell theory of aging is likely related to other theories. In addition, recent studies have started to reveal the essential roles of tissue-resident mesenchymal progenitors/stem cells/stromal cells in maintaining tissue homeostasis, and some evidence of their fundamental roles in the progression of aging has been presented. In this review, we discuss how stem cell and other theories connect to explain the progress of aging. In addition, we consider the mesenchymal progenitor theory of aging to describing the process of aging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 2 2%
Unknown 79 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 28%
Student > Master 13 16%
Student > Ph. D. Student 10 12%
Student > Bachelor 6 7%
Student > Doctoral Student 6 7%
Other 12 15%
Unknown 11 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 32 40%
Medicine and Dentistry 17 21%
Biochemistry, Genetics and Molecular Biology 12 15%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Arts and Humanities 1 1%
Other 6 7%
Unknown 11 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2014.
All research outputs
#12,897,392
of 22,751,628 outputs
Outputs from Frontiers in Cell and Developmental Biology
#2,012
of 8,967 outputs
Outputs of similar age
#104,825
of 224,799 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#5
of 11 outputs
Altmetric has tracked 22,751,628 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,967 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 224,799 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.