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X Demographics
Mendeley readers
Attention Score in Context
| Title |
G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling
|
|---|---|
| Published in |
Frontiers in Cell and Developmental Biology, December 2015
|
| DOI | 10.3389/fcell.2015.00076 |
| Pubmed ID | |
| Authors |
Nazanin F. Dolatshad, Nicola Hellen, Richard J. Jabbour, Sian E. Harding, Gabor Földes |
| Abstract |
Human pluripotent stem cell derivatives show promise as an in vitro platform to study a range of human cardiovascular diseases. A better understanding of the biology of stem cells and their cardiovascular derivatives will help to understand the strengths and limitations of this new model system. G-protein coupled receptors (GPCRs) are key regulators of stem cell maintenance and differentiation and have an important role in cardiovascular cell signaling. In this review, we will therefore describe the state of knowledge concerning the regulatory role of GPCRs in both the generation and function of pluripotent stem cell derived-cardiomyocytes, -endothelial, and -vascular smooth muscle cells. We will consider how far the in vitro disease models recapitulate authentic GPCR signaling and provide a useful basis for discovery of disease mechanisms or design of therapeutic strategies. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 4 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 48 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 16 | 33% |
| Student > Bachelor | 8 | 17% |
| Researcher | 7 | 15% |
| Student > Master | 5 | 10% |
| Other | 4 | 8% |
| Other | 6 | 13% |
| Unknown | 2 | 4% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 17 | 35% |
| Biochemistry, Genetics and Molecular Biology | 8 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Engineering | 4 | 8% |
| Medicine and Dentistry | 3 | 6% |
| Other | 7 | 15% |
| Unknown | 5 | 10% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2015.
All research outputs
#12,939,625
of 22,835,198 outputs
Outputs from Frontiers in Cell and Developmental Biology
#2,027
of 9,007 outputs
Outputs of similar age
#177,251
of 389,038 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#12
of 24 outputs
Altmetric has tracked 22,835,198 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,007 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 76% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 389,038 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.