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Transport Vesicle Tethering at the Trans Golgi Network: Coiled Coil Proteins in Action

Overview of attention for article published in Frontiers in Cell and Developmental Biology, March 2016
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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Title
Transport Vesicle Tethering at the Trans Golgi Network: Coiled Coil Proteins in Action
Published in
Frontiers in Cell and Developmental Biology, March 2016
DOI 10.3389/fcell.2016.00018
Pubmed ID
Authors

Pak-yan P. Cheung, Suzanne R. Pfeffer

Abstract

The Golgi complex is decorated with so-called Golgin proteins that share a common feature: a large proportion of their amino acid sequences are predicted to form coiled-coil structures. The possible presence of extensive coiled coils implies that these proteins are highly elongated molecules that can extend a significant distance from the Golgi surface. This property would help them to capture or trap inbound transport vesicles and to tether Golgi mini-stacks together. This review will summarize our current understanding of coiled coil tethers that are needed for the receipt of transport vesicles at the trans Golgi network (TGN). How do long tethering proteins actually catch vesicles? Golgi-associated, coiled coil tethers contain numerous binding sites for small GTPases, SNARE proteins, and vesicle coat proteins. How are these interactions coordinated and are any or all of them important for the tethering process? Progress toward understanding these questions and remaining, unresolved mysteries will be discussed.

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X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 69 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 36%
Researcher 8 12%
Student > Bachelor 7 10%
Student > Master 7 10%
Student > Doctoral Student 3 4%
Other 8 12%
Unknown 11 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 42%
Biochemistry, Genetics and Molecular Biology 23 33%
Chemical Engineering 1 1%
Immunology and Microbiology 1 1%
Economics, Econometrics and Finance 1 1%
Other 2 3%
Unknown 12 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 April 2016.
All research outputs
#13,767,344
of 22,852,911 outputs
Outputs from Frontiers in Cell and Developmental Biology
#2,519
of 9,030 outputs
Outputs of similar age
#150,085
of 299,390 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#15
of 32 outputs
Altmetric has tracked 22,852,911 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,030 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,390 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.