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Xenopus Oocyte As a Model System to Study Store-Operated Ca2+ Entry (SOCE)

Overview of attention for article published in Frontiers in Cell and Developmental Biology, June 2016
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Title
Xenopus Oocyte As a Model System to Study Store-Operated Ca2+ Entry (SOCE)
Published in
Frontiers in Cell and Developmental Biology, June 2016
DOI 10.3389/fcell.2016.00066
Pubmed ID
Authors

Raphaël Courjaret, Khaled Machaca

Abstract

Store-operated Ca(2+) entry (SOCE) is a ubiquitous Ca(2+) influx pathway at the cell membrane that is regulated by Ca(2+) content in intracellular stores. SOCE is important for a multitude of physiological processes, including muscle development, T-cell activation, and fertilization. Therefore, understanding the molecular regulation of SOCE is imperative. SOCE activation requires conformational and spatial changes in proteins located in both the endoplasmic reticulum and plasma membrane. This leads to the generation of an ionic current of very small amplitude. Both biochemical and electrophysiological parameters of SOCE can be difficult to record in small mammalian cells. In this protocol we present the different methodologies that enable the study of SOCE in a unique model system, the frog oocyte, which provides several advantages and have contributed significantly to our understanding of SOCE regulation.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Student > Doctoral Student 2 13%
Student > Ph. D. Student 2 13%
Lecturer > Senior Lecturer 1 7%
Other 1 7%
Other 2 13%
Unknown 4 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 20%
Agricultural and Biological Sciences 3 20%
Physics and Astronomy 1 7%
Medicine and Dentistry 1 7%
Chemistry 1 7%
Other 0 0%
Unknown 6 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 July 2016.
All research outputs
#13,984,762
of 22,879,161 outputs
Outputs from Frontiers in Cell and Developmental Biology
#2,563
of 9,056 outputs
Outputs of similar age
#195,865
of 352,727 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#17
of 40 outputs
Altmetric has tracked 22,879,161 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,056 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,727 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.