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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Oligodendrocyte, Astrocyte, and Microglia Crosstalk in Myelin Development, Damage, and Repair
|
|---|---|
| Published in |
Frontiers in Cell and Developmental Biology, June 2016
|
| DOI | 10.3389/fcell.2016.00071 |
| Pubmed ID | |
| Authors |
Helena S. Domingues, Camila C. Portugal, Renato Socodato, João B. Relvas |
| Abstract |
Oligodendrocytes are the myelinating glia of the central nervous system. Myelination of axons allows rapid saltatory conduction of nerve impulses and contributes to axonal integrity. Devastating neurological deficits caused by demyelinating diseases, such as multiple sclerosis, illustrate well the importance of the process. In this review, we focus on the positive and negative interactions between oligodendrocytes, astrocytes, and microglia during developmental myelination and remyelination. Even though many lines of evidence support a crucial role for glia crosstalk during these processes, the nature of such interactions is often neglected when designing therapeutics for repair of demyelinated lesions. Understanding the cellular and molecular mechanisms underlying glial cell communication and how they influence oligodendrocyte differentiation and myelination is fundamental to uncover novel therapeutic strategies for myelin repair. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 634 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Unknown | 633 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 139 | 22% |
| Student > Master | 96 | 15% |
| Student > Bachelor | 80 | 13% |
| Researcher | 72 | 11% |
| Student > Doctoral Student | 30 | 5% |
| Other | 80 | 13% |
| Unknown | 137 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 177 | 28% |
| Biochemistry, Genetics and Molecular Biology | 89 | 14% |
| Agricultural and Biological Sciences | 86 | 14% |
| Medicine and Dentistry | 40 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 3% |
| Other | 63 | 10% |
| Unknown | 162 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 February 2022.
All research outputs
#2,711,047
of 23,202,641 outputs
Outputs from Frontiers in Cell and Developmental Biology
#496
of 9,241 outputs
Outputs of similar age
#49,538
of 352,724 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#1
of 35 outputs
Altmetric has tracked 23,202,641 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,241 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,724 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.