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Septins As Modulators of Endo-Lysosomal Membrane Traffic

Overview of attention for article published in Frontiers in Cell and Developmental Biology, November 2016
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Title
Septins As Modulators of Endo-Lysosomal Membrane Traffic
Published in
Frontiers in Cell and Developmental Biology, November 2016
DOI 10.3389/fcell.2016.00124
Pubmed ID
Authors

Kyungyeun Song, Giulia Russo, Michael Krauss

Abstract

Septins constitute a family of GTP-binding proteins, which assemble into non-polar filaments in a nucleotide-dependent manner. These filaments can be recruited to negatively charged membrane surfaces. When associated with membranes septin filaments can act as diffusion barriers, which confine subdomains of distinct biological functions. In addition, they serve scaffolding roles by recruiting cytosolic proteins and other cytoskeletal elements. Septins have been implicated in a large variety of membrane-dependent processes, including cytokinesis, signaling, cell migration, and membrane traffic, and several family members have been implicated in disease. However, surprisingly little is known about the molecular mechanisms underlying their biological functions. This review summarizes evidence in support of regulatory roles of septins during endo-lysosomal sorting, with a particular focus on phosphoinositides, which serve as spatial landmarks guiding septin recruitment to distinct subcellular localizations.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 14 30%
Researcher 10 21%
Student > Doctoral Student 5 11%
Student > Bachelor 4 9%
Student > Master 4 9%
Other 3 6%
Unknown 7 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 19 40%
Agricultural and Biological Sciences 7 15%
Physics and Astronomy 3 6%
Neuroscience 2 4%
Medicine and Dentistry 2 4%
Other 6 13%
Unknown 8 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2016.
All research outputs
#15,393,913
of 22,901,818 outputs
Outputs from Frontiers in Cell and Developmental Biology
#3,991
of 9,074 outputs
Outputs of similar age
#195,608
of 311,571 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#21
of 40 outputs
Altmetric has tracked 22,901,818 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,074 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,571 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.