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Paying the Toll in Nuclear Reprogramming

Overview of attention for article published in Frontiers in Cell and Developmental Biology, August 2017
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Title
Paying the Toll in Nuclear Reprogramming
Published in
Frontiers in Cell and Developmental Biology, August 2017
DOI 10.3389/fcell.2017.00070
Pubmed ID
Authors

Chun Liu, Farhan Himmati, Nazish Sayed

Abstract

The ability to reverse lineage-committed cells toward pluripotent stem cells or to another cell type is one of the ultimate goals in regenerative medicine. We recently discovered that activation of innate immunity, through Toll-like receptor 3, is required during this conversion of cell fate by causing global changes in the expression and activity of epigenetic modifiers. Here we discuss, in a comprehensive manner, the recent studies on the role of innate immunity in nuclear reprogramming and transdifferentiation, the underlying mechanisms, and its role in regenerative medicine.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 15 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 20%
Other 2 13%
Student > Ph. D. Student 2 13%
Student > Doctoral Student 1 7%
Student > Bachelor 1 7%
Other 4 27%
Unknown 2 13%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 5 33%
Medicine and Dentistry 2 13%
Immunology and Microbiology 1 7%
Veterinary Science and Veterinary Medicine 1 7%
Neuroscience 1 7%
Other 1 7%
Unknown 4 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2017.
All research outputs
#17,911,821
of 22,997,544 outputs
Outputs from Frontiers in Cell and Developmental Biology
#4,343
of 9,111 outputs
Outputs of similar age
#228,608
of 318,832 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#21
of 27 outputs
Altmetric has tracked 22,997,544 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,111 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,832 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.