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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Extracellular Vesicle Flow Cytometry Analysis and Standardization
|
|---|---|
| Published in |
Frontiers in Cell and Developmental Biology, August 2017
|
| DOI | 10.3389/fcell.2017.00078 |
| Pubmed ID | |
| Authors |
Joshua A. Welsh, Judith A. Holloway, James S. Wilkinson, Nicola A. Englyst |
| Abstract |
The term extracellular vesicles (EVs) describes membranous vesicles derived from cells, ranging in diameter from 30 to 1,000 nm with the majority thought to be in the region of 100-150 nm. Due to their small diameter and complex and variable composition, conventional techniques have struggled to accurately count and phenotype EVs. Currently, EV characterization using high-resolution flow cytometry is the most promising method when compared to other currently available techniques, due to it being a high-throughput, single particle, multi-parameter analysis technique capable of analyzing a large range of particle diameters. Whilst high resolution flow cytometry promises detection of the full EV diameter range, standardization of light scattering and fluorescence data between different flow cytometers remains an problem. In this mini review, we will discuss the advances in high-resolution flow cytometry development and future direction of EV scatter and fluorescence standardization. Standardization and therefore reproducibility between research groups and instrumentation is lacking, hindering the validation of EVs use as diagnostic biomarkers and therapeutics. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 25% |
| United States | 1 | 25% |
| Switzerland | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 218 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 218 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 58 | 27% |
| Researcher | 36 | 17% |
| Student > Master | 31 | 14% |
| Student > Bachelor | 18 | 8% |
| Other | 10 | 5% |
| Other | 22 | 10% |
| Unknown | 43 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 67 | 31% |
| Agricultural and Biological Sciences | 24 | 11% |
| Medicine and Dentistry | 16 | 7% |
| Immunology and Microbiology | 15 | 7% |
| Engineering | 13 | 6% |
| Other | 31 | 14% |
| Unknown | 52 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2023.
All research outputs
#4,203,726
of 25,177,382 outputs
Outputs from Frontiers in Cell and Developmental Biology
#1,001
of 10,356 outputs
Outputs of similar age
#68,362
of 321,286 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#5
of 25 outputs
Altmetric has tracked 25,177,382 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,356 research outputs from this source. They receive a mean Attention Score of 3.6. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 321,286 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.