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Aging in a Relativistic Biological Space-Time

Overview of attention for article published in Frontiers in Cell and Developmental Biology, May 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

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17 X users

Citations

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32 Mendeley
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Title
Aging in a Relativistic Biological Space-Time
Published in
Frontiers in Cell and Developmental Biology, May 2018
DOI 10.3389/fcell.2018.00055
Pubmed ID
Authors

Davide Maestrini, Daniel Abler, Vikram Adhikarla, Saro Armenian, Sergio Branciamore, Nadia Carlesso, Ya-Huei Kuo, Guido Marcucci, Prativa Sahoo, Russell C. Rockne

Abstract

Here we present a theoretical and mathematical perspective on the process of aging. We extend the concepts of physical space and time to an abstract, mathematically-defined space, which we associate with a concept of "biological space-time" in which biological dynamics may be represented. We hypothesize that biological dynamics, represented as trajectories in biological space-time, may be used to model and study different rates of biological aging. As a consequence of this hypothesis, we show how dilation or contraction of time analogous to relativistic corrections of physical time resulting from accelerated or decelerated biological dynamics may be used to study precipitous or protracted aging. We show specific examples of how these principles may be used to model different rates of aging, with an emphasis on cancer in aging. We discuss how this theory may be tested or falsified, as well as novel concepts and implications of this theory that may improve our interpretation of biological aging.

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X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 32 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 16%
Researcher 5 16%
Student > Master 3 9%
Student > Doctoral Student 2 6%
Student > Bachelor 2 6%
Other 3 9%
Unknown 12 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 22%
Biochemistry, Genetics and Molecular Biology 4 13%
Medicine and Dentistry 3 9%
Engineering 2 6%
Psychology 1 3%
Other 2 6%
Unknown 13 41%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 March 2024.
All research outputs
#4,111,759
of 25,516,314 outputs
Outputs from Frontiers in Cell and Developmental Biology
#949
of 10,549 outputs
Outputs of similar age
#74,052
of 345,008 outputs
Outputs of similar age from Frontiers in Cell and Developmental Biology
#4
of 30 outputs
Altmetric has tracked 25,516,314 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,549 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 345,008 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.