You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Cancer wars: natural products strike back
|
|---|---|
| Published in |
Frontiers in Chemistry, May 2014
|
| DOI | 10.3389/fchem.2014.00020 |
| Pubmed ID | |
| Authors |
Christine Basmadjian, Qian Zhao, Embarek Bentouhami, Amel Djehal, Canan G. Nebigil, Roger A. Johnson, Maria Serova, Armand de Gramont, Sandrine Faivre, Eric Raymond, Laurent G. Désaubry |
| Abstract |
Natural products have historically been a mainstay source of anticancer drugs, but in the 90's they fell out of favor in pharmaceutical companies with the emergence of targeted therapies, which rely on antibodies or small synthetic molecules identified by high throughput screening. Although targeted therapies greatly improved the treatment of a few cancers, the benefit has remained disappointing for many solid tumors, which revitalized the interest in natural products. With the approval of rapamycin in 2007, 12 novel natural product derivatives have been brought to market. The present review describes the discovery and development of these new anticancer drugs and highlights the peculiarities of natural product and new trends in this exciting field of drug discovery. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 33% |
| Australia | 1 | 17% |
| Switzerland | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Scientists | 2 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 154 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 1% |
| India | 2 | 1% |
| Portugal | 1 | <1% |
| France | 1 | <1% |
| Italy | 1 | <1% |
| United States | 1 | <1% |
| Luxembourg | 1 | <1% |
| Unknown | 145 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 21% |
| Student > Master | 25 | 16% |
| Researcher | 21 | 14% |
| Student > Bachelor | 19 | 12% |
| Professor | 8 | 5% |
| Other | 29 | 19% |
| Unknown | 19 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 24% |
| Chemistry | 34 | 22% |
| Biochemistry, Genetics and Molecular Biology | 32 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 5% |
| Medicine and Dentistry | 5 | 3% |
| Other | 11 | 7% |
| Unknown | 28 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 February 2017.
All research outputs
#7,443,648
of 22,754,104 outputs
Outputs from Frontiers in Chemistry
#644
of 5,897 outputs
Outputs of similar age
#74,259
of 227,852 outputs
Outputs of similar age from Frontiers in Chemistry
#4
of 24 outputs
Altmetric has tracked 22,754,104 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,897 research outputs from this source. They receive a mean Attention Score of 2.0. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,852 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.