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Exposure to ergot alkaloids during gestation reduces fetal growth in sheep

Overview of attention for article published in Frontiers in Chemistry, August 2014
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Title
Exposure to ergot alkaloids during gestation reduces fetal growth in sheep
Published in
Frontiers in Chemistry, August 2014
DOI 10.3389/fchem.2014.00068
Pubmed ID
Authors

Susan K. Duckett, John G. Andrae, Scott L. Pratt

Abstract

Tall fescue [Lolium arundinaceum (Schreb.) Darbysh; Schedonorus phoenix (Scop.) Holub] is the primary cool season perennial grass in the eastern U.S. Most tall fescue contains an endophyte (Neotyphodium coenophialum), which produces ergot alkaloids that cause vasoconstriction and could restrict blood flow to the fetus in pregnant animals. The objective of this study was to examine fetal growth during maternal exposure to ergot alkaloids during gestation. Pregnant ewes (n = 16) were randomly assigned to one of two dietary treatments: (1) endophyte-infected (N. coenophialum) tall fescue seed (E+; 0.8 ug of ergovaline /g diet DM) and (2) endophyte-free tall fescue seed (E-; 0.0 ug of ergovaline/g diet DM). Birth weight of lambs was reduced by 37% for E+ compared to E-. Organ and muscle weights were also lighter for E+ than E-. Exposure to ergot alkaloids in utero reduces fetal growth and muscle development.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 22 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 18%
Student > Ph. D. Student 3 14%
Student > Master 3 14%
Student > Bachelor 2 9%
Student > Postgraduate 2 9%
Other 5 23%
Unknown 3 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 36%
Veterinary Science and Veterinary Medicine 5 23%
Medicine and Dentistry 4 18%
Biochemistry, Genetics and Molecular Biology 1 5%
Engineering 1 5%
Other 0 0%
Unknown 3 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2014.
All research outputs
#18,376,056
of 22,760,687 outputs
Outputs from Frontiers in Chemistry
#2,197
of 5,897 outputs
Outputs of similar age
#168,218
of 235,897 outputs
Outputs of similar age from Frontiers in Chemistry
#16
of 34 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,897 research outputs from this source. They receive a mean Attention Score of 2.0. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,897 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.