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Surface Analysis of Gold Nanoparticles Functionalized with Thiol-Modified Glucose SAMs for Biosensor Applications

Overview of attention for article published in Frontiers in Chemistry, February 2016
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174 Mendeley
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Title
Surface Analysis of Gold Nanoparticles Functionalized with Thiol-Modified Glucose SAMs for Biosensor Applications
Published in
Frontiers in Chemistry, February 2016
DOI 10.3389/fchem.2016.00008
Pubmed ID
Authors

Valentina Spampinato, Maria Antonietta Parracino, Rita La Spina, Francois Rossi, Giacomo Ceccone

Abstract

In this work, Time of Flight Secondary Ion Mass Spectrometry (ToF-SIMS), Principal Component Analysis (PCA) and X-ray Photoelectron Spectroscopy (XPS) have been used to characterize the surface chemistry of gold substrates before and after functionalization with thiol-modified glucose self-assembled monolayers and subsequent biochemical specific recognition of maltose binding protein (MBP). The results indicate that the surface functionalization is achieved both on flat and nanoparticles gold substrates thus showing the potential of the developed system as biodetection platform. Moreover, the method presented here has been found to be a sound and valid approach to characterize the surface chemistry of nanoparticles functionalized with large molecules. Both techniques were proved to be very useful tools for monitoring all the functionalization steps, including the investigation of the biological behavior of the glucose-modified particles in the presence of the maltose binding protein.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 174 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Indonesia 1 <1%
Spain 1 <1%
United States 1 <1%
Unknown 171 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 31 18%
Student > Master 29 17%
Student > Bachelor 19 11%
Researcher 17 10%
Student > Doctoral Student 11 6%
Other 24 14%
Unknown 43 25%
Readers by discipline Count As %
Chemistry 48 28%
Engineering 17 10%
Materials Science 16 9%
Biochemistry, Genetics and Molecular Biology 10 6%
Chemical Engineering 9 5%
Other 26 15%
Unknown 48 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2016.
All research outputs
#18,345,259
of 23,567,572 outputs
Outputs from Frontiers in Chemistry
#1,784
of 6,195 outputs
Outputs of similar age
#204,519
of 298,927 outputs
Outputs of similar age from Frontiers in Chemistry
#7
of 14 outputs
Altmetric has tracked 23,567,572 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,195 research outputs from this source. They receive a mean Attention Score of 2.1. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,927 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.