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Mendeley readers
Attention Score in Context
| Title |
Modified Nucleoside Triphosphates for In-vitro Selection Techniques
|
|---|---|
| Published in |
Frontiers in Chemistry, May 2016
|
| DOI | 10.3389/fchem.2016.00018 |
| Pubmed ID | |
| Authors |
María A. Dellafiore, Javier M. Montserrat, Adolfo M. Iribarren |
| Abstract |
The development of SELEX (Selective Enhancement of Ligands by Exponential Enrichment) provides a powerful tool for the search of functional oligonucleotides with the ability to bind ligands with high affinity and selectivity (aptamers) and for the discovery of nucleic acid sequences with diverse enzymatic activities (ribozymes and DNAzymes). This technique has been extensively applied to the selection of natural DNA or RNA molecules but, in order to improve chemical and structural diversity as well as for particular applications where further chemical or biological stability is necessary, the extension of this strategy to modified oligonucleotides is desirable. Taking into account these needs, this review intends to collect the research carried out during the past years, focusing mainly on the use of modified nucleotides in SELEX and the development of mutant enzymes for broadening nucleoside triphosphates acceptance. In addition, comments regarding the synthesis of modified nucleoside triphosphate will be briefly discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 88 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 28% |
| Researcher | 18 | 20% |
| Student > Doctoral Student | 5 | 6% |
| Student > Postgraduate | 5 | 6% |
| Student > Bachelor | 4 | 5% |
| Other | 13 | 15% |
| Unknown | 18 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 29 | 33% |
| Chemistry | 25 | 28% |
| Agricultural and Biological Sciences | 6 | 7% |
| Chemical Engineering | 2 | 2% |
| Engineering | 2 | 2% |
| Other | 4 | 5% |
| Unknown | 20 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 May 2016.
All research outputs
#20,323,943
of 22,867,327 outputs
Outputs from Frontiers in Chemistry
#2,918
of 5,958 outputs
Outputs of similar age
#253,262
of 298,972 outputs
Outputs of similar age from Frontiers in Chemistry
#14
of 14 outputs
Altmetric has tracked 22,867,327 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,958 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,972 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 14 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.