Title |
Nanochemistry of Protein-Based Delivery Agents
|
---|---|
Published in |
Frontiers in Chemistry, July 2016
|
DOI | 10.3389/fchem.2016.00031 |
Pubmed ID | |
Authors |
Subin R. C. K. Rajendran, Chibuike C. Udenigwe, Rickey Y. Yada |
Abstract |
The past decade has seen an increased interest in the conversion of food proteins into functional biomaterials, including their use for loading and delivery of physiologically active compounds such as nutraceuticals and pharmaceuticals. Proteins possess a competitive advantage over other platforms for the development of nanodelivery systems since they are biocompatible, amphipathic, and widely available. Proteins also have unique molecular structures and diverse functional groups that can be selectively modified to alter encapsulation and release properties. A number of physical and chemical methods have been used for preparing protein nanoformulations, each based on different underlying protein chemistry. This review focuses on the chemistry of the reorganization and/or modification of proteins into functional nanostructures for delivery, from the perspective of their preparation, functionality, stability and physiological behavior. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Canada | 1 | 20% |
Switzerland | 1 | 20% |
Unknown | 3 | 60% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 70 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 14 | 20% |
Student > Master | 12 | 17% |
Student > Ph. D. Student | 8 | 11% |
Student > Doctoral Student | 4 | 6% |
Student > Postgraduate | 4 | 6% |
Other | 11 | 16% |
Unknown | 17 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 19% |
Biochemistry, Genetics and Molecular Biology | 8 | 11% |
Chemistry | 7 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 10% |
Medicine and Dentistry | 3 | 4% |
Other | 8 | 11% |
Unknown | 24 | 34% |