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Self-Assembly of a [1 + 1] Ionic Hexagonal Macrocycle and Its Antiproliferative Activity

Overview of attention for article published in Frontiers in Chemistry, April 2018
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Title
Self-Assembly of a [1 + 1] Ionic Hexagonal Macrocycle and Its Antiproliferative Activity
Published in
Frontiers in Chemistry, April 2018
DOI 10.3389/fchem.2018.00087
Pubmed ID
Authors

Khushwant Singh, Ankit Gangrade, Sourav Bhowmick, Achintya Jana, Biman B. Mandal, Neeladri Das

Abstract

A unique irregular hexagon was self-assembled using an organic donor clip (bearing terminal pyridyl units) and a complementary organometallic acceptor clip. The resulting metallamacrocycle was characterized by multinuclear NMR, mass spectrometry, and elemental analyses. Molecular modeling confirmed hexagonal shaped cavity for this metallamacrocycle which is a unique example of a discrete hexagonal framework self-assembled from only two building blocks. Cytotoxicity of the Pt-based acceptor tecton and the self-assembled PtII-based macrocycle was evaluated using three cancer cell lines and results were compared with cisplatin. Results confirmed a positive effect of the metallamacrocycle formation on cell growth inhibition.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 30%
Other 2 20%
Professor > Associate Professor 2 20%
Researcher 1 10%
Student > Doctoral Student 1 10%
Other 0 0%
Unknown 1 10%
Readers by discipline Count As %
Chemistry 3 30%
Materials Science 2 20%
Decision Sciences 1 10%
Biochemistry, Genetics and Molecular Biology 1 10%
Engineering 1 10%
Other 0 0%
Unknown 2 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 April 2018.
All research outputs
#20,478,782
of 23,039,416 outputs
Outputs from Frontiers in Chemistry
#2,936
of 6,013 outputs
Outputs of similar age
#290,542
of 329,118 outputs
Outputs of similar age from Frontiers in Chemistry
#61
of 136 outputs
Altmetric has tracked 23,039,416 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,013 research outputs from this source. They receive a mean Attention Score of 2.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,118 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 136 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.