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A Five-Component Biginelli-Diels-Alder Cascade Reaction

Overview of attention for article published in Frontiers in Chemistry, August 2018
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  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
A Five-Component Biginelli-Diels-Alder Cascade Reaction
Published in
Frontiers in Chemistry, August 2018
DOI 10.3389/fchem.2018.00376
Pubmed ID
Authors

Taber S. Maskrey, Madeline C. Frischling, Mikhaila L. Rice, Peter Wipf

Abstract

A new multi-component condensation was discovered during the reaction of a urea, β-keto ester, and formaldehyde. In the presence of catalytic indium bromide, a Biginelli dihydropyrimidinone intermediate was further converted to a five-component condensation product through a formal hetero Diels-Alder reaction. The product structure was confirmed by NMR and NOE analysis, and the proposed stepwise mechanism was supported by the reaction of the Biginelli intermediate with ethyl 2-methylene-3-oxobutanoate.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 23 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 22%
Researcher 5 22%
Student > Ph. D. Student 3 13%
Professor > Associate Professor 2 9%
Other 1 4%
Other 2 9%
Unknown 5 22%
Readers by discipline Count As %
Chemistry 13 57%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Agricultural and Biological Sciences 1 4%
Biochemistry, Genetics and Molecular Biology 1 4%
Medicine and Dentistry 1 4%
Other 1 4%
Unknown 5 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2018.
All research outputs
#15,017,219
of 23,100,534 outputs
Outputs from Frontiers in Chemistry
#1,210
of 6,040 outputs
Outputs of similar age
#199,932
of 334,198 outputs
Outputs of similar age from Frontiers in Chemistry
#49
of 193 outputs
Altmetric has tracked 23,100,534 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,040 research outputs from this source. They receive a mean Attention Score of 2.0. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 334,198 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 193 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.