You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
Inhalational monkeypox virus infection in cynomolgus macaques
|
|---|---|
| Published in |
Frontiers in Cellular and Infection Microbiology, January 2012
|
| DOI | 10.3389/fcimb.2012.00117 |
| Pubmed ID | |
| Authors |
Roy E. Barnewall, David A. Fisher, Ashley B. Robertson, Pauline A. Vales, Katherine A. Knostman, John E. Bigger |
| Abstract |
An inhalation exposure system was characterized to deliver aerosolized monkeypox virus (MPXV), and a non-human primate (NHP) inhalation monkeypox model was developed in cynomolgus macaques. A head-only aerosol exposure system was characterized, and two sampling methods were evaluated: liquid impingement via an impinger and impaction via a gelatin filter. The aerosol concentrations obtained with the gelatin filter and impinger were virtually identical, indicating that either method is acceptable for sampling aerosols containing MPXV. The mass median aerodynamic diameter (MMAD) for individual aerosol tests in the aerosol system characterization and the NHP study ranged from 1.08 to 1.15 μm, indicating that the aerosol particles were of a sufficient size to reach the alveoli. Six cynomolgus macaques (four male and two female) were used on study. The animals were aerosol exposed with MPXV and received doses between 2.51 × 10(4) to 9.28 × 10(5) plaque forming units (PFUs) inhaled. Four of the six animals died or were euthanized due to their moribund conditions. Both animals that received the lowest exposure doses survived to the end of the observation period. The inhalation LD(50) was determined to be approximately 7.8 × 10(4) pfu inhaled. These data demonstrate that an inhalation MPXV infection model has been developed in the cynomolgus macaque with disease course and lethal dose similar to previously published data. |
X Demographics
The data shown below were collected from the profiles of 118 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 17 | 14% |
| Australia | 6 | 5% |
| Canada | 6 | 5% |
| United Kingdom | 5 | 4% |
| Netherlands | 3 | 3% |
| Germany | 3 | 3% |
| Brazil | 2 | 2% |
| Poland | 1 | <1% |
| Ireland | 1 | <1% |
| Other | 3 | 3% |
| Unknown | 71 | 60% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 99 | 84% |
| Scientists | 8 | 7% |
| Practitioners (doctors, other healthcare professionals) | 7 | 6% |
| Science communicators (journalists, bloggers, editors) | 4 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 30 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 4 | 13% |
| Researcher | 3 | 10% |
| Professor > Associate Professor | 3 | 10% |
| Student > Doctoral Student | 2 | 7% |
| Student > Bachelor | 2 | 7% |
| Other | 4 | 13% |
| Unknown | 12 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 20% |
| Agricultural and Biological Sciences | 3 | 10% |
| Veterinary Science and Veterinary Medicine | 2 | 7% |
| Immunology and Microbiology | 2 | 7% |
| Nursing and Health Professions | 1 | 3% |
| Other | 1 | 3% |
| Unknown | 15 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 63. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 October 2022.
All research outputs
#694,310
of 25,795,662 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#113
of 8,275 outputs
Outputs of similar age
#3,693
of 251,992 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#4
of 114 outputs
Altmetric has tracked 25,795,662 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,275 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,992 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.