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The role of eicosanoids in experimental Lyme arthritis

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, May 2014
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Title
The role of eicosanoids in experimental Lyme arthritis
Published in
Frontiers in Cellular and Infection Microbiology, May 2014
DOI 10.3389/fcimb.2014.00069
Pubmed ID
Authors

Carmela L. Pratt, Charles R. Brown

Abstract

Experimental Lyme arthritis is an inflammatory arthritis caused by infection of mice with the spirochete, Borrelia burgdorferi. It recapitulates many of the disease parameters seen in human patients with Lyme arthritis, and thus serves as a model system for the investigation of disease pathogenesis. While much progress has been made in defining components of the immune response to Borrelia infection, an overall understanding of the host response leading to arthritis resistance or susceptibility remains elusive. In this review, we will focus on recent advancements of our understanding of the roles of eicosanoids as inflammatory mediators in the regulation of experimental Lyme arthritis. Eicosanoids, such as PGE2 and LTB4, are powerful regulators of inflammatory responses and thus may be important mediators of Lyme arthritis.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 16%
Student > Master 6 16%
Student > Ph. D. Student 6 16%
Professor 3 8%
Researcher 3 8%
Other 4 11%
Unknown 10 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 8 21%
Medicine and Dentistry 4 11%
Immunology and Microbiology 4 11%
Biochemistry, Genetics and Molecular Biology 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 5 13%
Unknown 13 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2014.
All research outputs
#18,373,576
of 22,757,090 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#4,778
of 6,348 outputs
Outputs of similar age
#163,116
of 226,672 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#17
of 28 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,348 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 226,672 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.