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What RNAi screens in model organisms revealed about microbicidal response in mammals?

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

blogs
1 blog
twitter
7 X users

Readers on

mendeley
28 Mendeley
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Title
What RNAi screens in model organisms revealed about microbicidal response in mammals?
Published in
Frontiers in Cellular and Infection Microbiology, January 2015
DOI 10.3389/fcimb.2014.00184
Pubmed ID
Authors

Prasad Abnave, Filippo Conti, Cedric Torre, Eric Ghigo

Abstract

The strategies evolved by pathogens to infect hosts and the mechanisms used by the host to eliminate intruders are highly complex. Because several biological pathways and processes are conserved across model organisms, these organisms have been used for many years to elucidate and understand the mechanisms of the host-pathogen relationship and particularly to unravel the molecular processes enacted by the host to kill pathogens. The emergence of RNA interference (RNAi) and the ability to apply it toward studies in model organisms have allowed a breakthrough in the elucidation of host-pathogen interactions. The aim of this mini-review is to highlight and describe recent breakthroughs in the field of host-pathogen interactions using RNAi screens of model organisms. We will focus specifically on the model organisms Drosophila melanogaster, Caenorhabditis elegans, and Danio rerio. Moreover, a recent study examining the immune system of planarian will be discussed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Unknown 27 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Student > Ph. D. Student 5 18%
Student > Bachelor 4 14%
Professor > Associate Professor 4 14%
Lecturer 2 7%
Other 5 18%
Unknown 2 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 57%
Biochemistry, Genetics and Molecular Biology 5 18%
Business, Management and Accounting 1 4%
Computer Science 1 4%
Materials Science 1 4%
Other 1 4%
Unknown 3 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2018.
All research outputs
#3,325,874
of 23,577,654 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#667
of 6,876 outputs
Outputs of similar age
#48,391
of 356,142 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#5
of 46 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,876 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 356,142 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 46 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.