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Differential induction of total IgE by two Salmonella enterica serotypes

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, May 2015
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Title
Differential induction of total IgE by two Salmonella enterica serotypes
Published in
Frontiers in Cellular and Infection Microbiology, May 2015
DOI 10.3389/fcimb.2015.00043
Pubmed ID
Authors

Zhanna A. Ktsoyan, Mkhitar S. Mkrtchyan, Magdalina K. Zakharyan, Armine A. Mnatsakanyan, Karine A. Arakelova, Zaruhi U. Gevorgyan, Lusntag A. Ktsoyan, Anahit Ì. Sedrakyan, Alvard I. Hovhannisyan, Karine A. Ghazaryan, Anna S. Boyajyan, Rustam I. Aminov

Abstract

The main goal of this study was to establish how the inflammation caused by infection with two different Salmonella enterica serotypes, S. Typhimurium and S. Enteritidis, may lead to the predisposition to allergy as measured by total IgE level in the blood. Infection by S. Typhimurium did not affect the systemic IgE concentration while in S. Enteritidis-infected patients there was a significant 3.5-fold increase. This effect was especially profound in patients >4 years old, with up to the 8-fold increase above the norm. The degree of dysbiosis in these two infections measured with the comparative counts of cultivated bacteria showed an inverse relationship with the IgE concentration. Earlier we reported the elevated level of IL-17 in patients infected by S. Enteritidis. In the current study a significant correlation was found between the concentrations of IL-17 and IgE suggesting a possible role played by this cytokine in triggering the production of IgE in response to S. Enteritidis infection.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 2 14%
Librarian 1 7%
Other 1 7%
Student > Ph. D. Student 1 7%
Student > Bachelor 1 7%
Other 2 14%
Unknown 6 43%
Readers by discipline Count As %
Medicine and Dentistry 2 14%
Biochemistry, Genetics and Molecular Biology 1 7%
Agricultural and Biological Sciences 1 7%
Nursing and Health Professions 1 7%
Immunology and Microbiology 1 7%
Other 1 7%
Unknown 7 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 June 2022.
All research outputs
#14,719,073
of 22,653,392 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#3,099
of 6,269 outputs
Outputs of similar age
#147,332
of 266,549 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#7
of 13 outputs
Altmetric has tracked 22,653,392 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,269 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 266,549 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.