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Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, November 2015
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  • Good Attention Score compared to outputs of the same age and source (71st percentile)

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Title
Mechanisms of Disease: Host-Pathogen Interactions between Burkholderia Species and Lung Epithelial Cells
Published in
Frontiers in Cellular and Infection Microbiology, November 2015
DOI 10.3389/fcimb.2015.00080
Pubmed ID
Authors

Jonathan David, Rachel E. Bell, Graeme C. Clark

Abstract

Members of the Burkholderia species can cause a range of severe, often fatal, respiratory diseases. A variety of in vitro models of infection have been developed in an attempt to elucidate the mechanism by which Burkholderia spp. gain entry to and interact with the body. The majority of studies have tended to focus on the interaction of bacteria with phagocytic cells with a paucity of information available with regard to the lung epithelium. However, the lung epithelium is becoming more widely recognized as an important player in innate immunity and the early response to infections. Here we review the complex relationship between Burkholderia species and epithelial cells with an emphasis on the most pathogenic species, Burkholderia pseudomallei and Burkholderia mallei. The current gaps in knowledge in our understanding are highlighted along with the epithelial host-pathogen interactions that offer potential opportunities for therapeutic intervention.

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The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 83 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 13 16%
Student > Master 12 14%
Student > Ph. D. Student 11 13%
Researcher 9 11%
Student > Doctoral Student 6 7%
Other 16 19%
Unknown 16 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 23%
Immunology and Microbiology 15 18%
Biochemistry, Genetics and Molecular Biology 12 14%
Medicine and Dentistry 7 8%
Engineering 3 4%
Other 8 10%
Unknown 19 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 June 2016.
All research outputs
#13,900,658
of 23,577,761 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#2,375
of 6,875 outputs
Outputs of similar age
#189,969
of 390,031 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#20
of 71 outputs
Altmetric has tracked 23,577,761 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,875 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 390,031 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 49th percentile – i.e., 49% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 71 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.