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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Staphylococcus aureus vs. Osteoblast: Relationship and Consequences in Osteomyelitis
|
|---|---|
| Published in |
Frontiers in Cellular and Infection Microbiology, November 2015
|
| DOI | 10.3389/fcimb.2015.00085 |
| Pubmed ID | |
| Authors |
Jérôme Josse, Frédéric Velard, Sophie C. Gangloff |
| Abstract |
Bone cells, namely osteoblasts and osteoclasts work in concert and are responsible for bone extracellular matrix formation and resorption. This homeostasis is, in part, altered during infections by Staphylococcus aureus through the induction of various responses from the osteoblasts. This includes the over-production of chemokines, cytokines and growth factors, thus suggesting a role for these cells in both innate and adaptive immunity. S. aureus decreases the activity and viability of osteoblasts, by induction of apoptosis-dependent and independent mechanisms. The tight relationship between osteoclasts and osteoblasts is also modulated by S. aureus infection. The present review provides a survey of the relevant literature discussing the important aspects of S. aureus and osteoblast interaction as well as the ability for antimicrobial peptides to kill intra-osteoblastic S. aureus, hence emphasizing the necessity for new anti-infectious therapeutics. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| Unknown | 2 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 218 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 218 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 42 | 19% |
| Student > Master | 32 | 15% |
| Researcher | 26 | 12% |
| Student > Doctoral Student | 15 | 7% |
| Student > Bachelor | 13 | 6% |
| Other | 34 | 16% |
| Unknown | 56 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 41 | 19% |
| Immunology and Microbiology | 27 | 12% |
| Biochemistry, Genetics and Molecular Biology | 22 | 10% |
| Agricultural and Biological Sciences | 16 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 4% |
| Other | 35 | 16% |
| Unknown | 68 | 31% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2018.
All research outputs
#6,426,876
of 22,834,308 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#1,265
of 6,393 outputs
Outputs of similar age
#100,763
of 387,189 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#10
of 78 outputs
Altmetric has tracked 22,834,308 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 6,393 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 387,189 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.