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New Concepts in Malaria Pathogenesis: The Role of the Renin-Angiotensin System

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, January 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

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84 X users

Citations

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19 Dimensions

Readers on

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75 Mendeley
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Title
New Concepts in Malaria Pathogenesis: The Role of the Renin-Angiotensin System
Published in
Frontiers in Cellular and Infection Microbiology, January 2016
DOI 10.3389/fcimb.2015.00103
Pubmed ID
Authors

Leandro S. Silva, João Luiz Silva-Filho, Celso Caruso-Neves, Ana Acacia S. Pinheiro

Abstract

Malaria is a worldwide health problem leading the death of millions of people. The disease is induced by different species of protozoa parasites from the genus Plasmodium. In humans, Plasmodium falciparum is the most dangerous species responsible for severe disease. Despite all efforts to establish the pathogenesis of malaria, it is far from being fully understood. In addition, resistance to existing drugs has developed in several strains and the development of new effective compounds to fight these parasites is a major issue. Recent discoveries indicate the potential role of the renin-angiotensin system (RAS) in malaria infection. Angiotensin receptors have not been described in the parasite genome, however several reports in the literature suggest a direct effect of angiotensin-derived peptides on different aspects of the host-parasite interaction. The aim of this review is to highlight new findings on the involvement of the RAS in parasite development and in the regulation of the host immune response in an attempt to expand our knowledge of the pathogenesis of this disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 84 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 75 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Nigeria 1 1%
Canada 1 1%
Brazil 1 1%
Unknown 71 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 19%
Student > Ph. D. Student 9 12%
Student > Doctoral Student 8 11%
Student > Bachelor 8 11%
Student > Master 8 11%
Other 15 20%
Unknown 13 17%
Readers by discipline Count As %
Medicine and Dentistry 23 31%
Biochemistry, Genetics and Molecular Biology 13 17%
Agricultural and Biological Sciences 9 12%
Immunology and Microbiology 6 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 3 4%
Unknown 18 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 52. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2023.
All research outputs
#831,533
of 25,864,668 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#143
of 8,298 outputs
Outputs of similar age
#14,247
of 402,147 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#2
of 42 outputs
Altmetric has tracked 25,864,668 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,298 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.6. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 402,147 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.