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Epigenetics in Schistosomes: What We Know and What We Need Know

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, November 2016
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Title
Epigenetics in Schistosomes: What We Know and What We Need Know
Published in
Frontiers in Cellular and Infection Microbiology, November 2016
DOI 10.3389/fcimb.2016.00149
Pubmed ID
Authors

Weiwei Liu

Abstract

Schistosomes are metazoan parasites and can cause schistosomiasis. Epigenetic modifications include DNA methylation, histone modifications and non-coding RNAs. Some enzymes involved in epigenetic modification and microRNA processes have been developed as drugs to treat the disease. Compared with humans and vertebrates, an in-depth understanding of epigenetic modifications in schistosomes is starting to be realized. DNA methylation, histone modifications and non-coding RNAs play important roles in the development and reproduction of schistosomes and in interactions between the host and schistosomes. Therefore, exploring and investigating the epigenetic modifications in schistosomes will facilitate drug development and therapy for schistosomiasis. Here, we review the role of epigenetic modifications in the development, growth and reproduction of schistosomes, and the interactions between the host and schistosome. We further discuss potential epigenetic targets for drug discovery for the treatment of schistosomiasis.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 25%
Student > Bachelor 7 16%
Researcher 5 11%
Librarian 2 5%
Student > Master 2 5%
Other 5 11%
Unknown 12 27%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 25%
Agricultural and Biological Sciences 6 14%
Chemistry 4 9%
Medicine and Dentistry 4 9%
Immunology and Microbiology 2 5%
Other 3 7%
Unknown 14 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2017.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#6,021
of 8,068 outputs
Outputs of similar age
#244,250
of 316,741 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#50
of 88 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,068 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,741 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.