Title |
A Long Journey Ahead: Long Non-coding RNAs in Bacterial Infections
|
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Published in |
Frontiers in Cellular and Infection Microbiology, March 2017
|
DOI | 10.3389/fcimb.2017.00095 |
Pubmed ID | |
Authors |
Jennifer zur Bruegge, Ralf Einspanier, Soroush Sharbati |
Abstract |
Bacterial pathogens have coevolved with their hosts and acquired strategies to circumvent defense mechanisms of host cells. It was shown that bacteria interfere with the expression of mammalian microRNAs to modify immune signaling, autophagy, or the apoptotic machinery. Recently, a new class of regulatory RNAs, long non-coding RNAs (lncRNAs), was reported to have a pivotal role in the regulation of eukaryotic gene expression. A growing body of literature reports on specific involvement of lncRNAs in the host cell response toward bacterial infections. This mini review summarizes recent data that focuses on lncRNA function in host cells during bacterial infection and provides a perspective where future research in this regard may be going. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 13% |
France | 1 | 13% |
Netherlands | 1 | 13% |
Japan | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 50% |
Scientists | 4 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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India | 1 | 1% |
Unknown | 79 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 15 | 19% |
Researcher | 10 | 13% |
Student > Master | 9 | 11% |
Student > Bachelor | 8 | 10% |
Professor > Associate Professor | 5 | 6% |
Other | 12 | 15% |
Unknown | 21 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 21 | 26% |
Agricultural and Biological Sciences | 17 | 21% |
Immunology and Microbiology | 9 | 11% |
Medicine and Dentistry | 7 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Other | 4 | 5% |
Unknown | 20 | 25% |