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Metabolic Adaptations of Uropathogenic E. coli in the Urinary Tract

Overview of attention for article published in Frontiers in Cellular and Infection Microbiology, June 2017
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  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

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1 news outlet
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17 X users

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295 Mendeley
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Title
Metabolic Adaptations of Uropathogenic E. coli in the Urinary Tract
Published in
Frontiers in Cellular and Infection Microbiology, June 2017
DOI 10.3389/fcimb.2017.00241
Pubmed ID
Authors

Riti Mann, Daniel G. Mediati, Iain G. Duggin, Elizabeth J. Harry, Amy L. Bottomley

Abstract

Escherichia coli ordinarily resides in the lower gastrointestinal tract in humans, but some strains, known as Uropathogenic E. coli (UPEC), are also adapted to the relatively harsh environment of the urinary tract. Infections of the urine, bladder and kidneys by UPEC may lead to potentially fatal bloodstream infections. To survive this range of conditions, UPEC strains must have broad and flexible metabolic capabilities and efficiently utilize scarce essential nutrients. Whole-organism (or "omics") methods have recently provided significant advances in our understanding of the importance of metabolic adaptation in the success of UPECs. Here we describe the nutritional and metabolic requirements for UPEC infection in these environments, and focus on particular metabolic responses and adaptations of UPEC that appear to be essential for survival in the urinary tract.

X Demographics

X Demographics

The data shown below were collected from the profiles of 17 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 295 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 295 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 50 17%
Student > Master 41 14%
Student > Bachelor 41 14%
Researcher 28 9%
Other 11 4%
Other 33 11%
Unknown 91 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 50 17%
Immunology and Microbiology 44 15%
Agricultural and Biological Sciences 26 9%
Medicine and Dentistry 21 7%
Pharmacology, Toxicology and Pharmaceutical Science 9 3%
Other 49 17%
Unknown 96 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 November 2018.
All research outputs
#1,478,818
of 23,577,654 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#226
of 6,873 outputs
Outputs of similar age
#30,648
of 318,294 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#7
of 192 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 6,873 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 318,294 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 192 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.