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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Biofilm Formation in Klebsiella pneumoniae Bacteremia Strains Was Found to be Associated with CC23 and the Presence of wcaG
|
|---|---|
| Published in |
Frontiers in Cellular and Infection Microbiology, February 2018
|
| DOI | 10.3389/fcimb.2018.00021 |
| Pubmed ID | |
| Authors |
Jin-xin Zheng, Zhi-wei Lin, Chen Chen, Zhong Chen, Fo-jun Lin, Yang Wu, Si-yu Yang, Xiang Sun, Wei-ming Yao, Duo-yun Li, Zhi-jian Yu, Jia-lin Jin, Di Qu, Qi-wen Deng |
| Abstract |
Klebsiella pneumoniae bacteremia biofilm traits and distribution characteristics have not been clarified. This study aimed to determine the prevalence and characteristics ofK. pneumoniaebacteremia biofilm formation (BF) and to explore the virulence factors associated withK. pneumoniaeBF. A total of 250K. pneumoniaebacteremia isolates were collected from patients in Shenzhen and Shanghai, China. Virulence genes in their genomes were detected by PCR. The isolates were subjected to multilocus sequence typing (MLST) and clonal complex (CC) classification based on housekeeping genes. Biofilms were detected by crystal violet staining. Greater BF was observed in isolates from young adults (<40 years old) than in those from seniors (≥65 years old;P= 0.002). MLST yielded 65 different sequence types (STs), with the most represented STs being ST11, ST23, and ST65, and the main CCs were CC23 and CC65; CC23 isolates exhibited greater BF than CC65 or ST11 isolates (bothP< 0.001). BF was more pronounced amongmagA(K1), aero+,rmpA+,rmpA2+,allS+,wcaG+, andiutA+ isolates than in isolates that were negative for these virulence factors. Multivariate regression analysis revealed onlywcaGas an independent risk factor for BF (odds ratio 11.426,P< 0.001), and BF was decreased whenwcaGwas silenced by antisense RNA. In conclusion, BF inK. pneumoniaebacteremia isolates was found to be associated with CC23 classification and the presence of thewcaGvirulence factor gene. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Libya | 1 | 17% |
| Australia | 1 | 17% |
| Nepal | 1 | 17% |
| Switzerland | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 4 | 67% |
| Members of the public | 2 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 165 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 165 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 18 | 11% |
| Student > Ph. D. Student | 16 | 10% |
| Researcher | 14 | 8% |
| Student > Master | 12 | 7% |
| Student > Doctoral Student | 9 | 5% |
| Other | 35 | 21% |
| Unknown | 61 | 37% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 28 | 17% |
| Immunology and Microbiology | 28 | 17% |
| Medicine and Dentistry | 15 | 9% |
| Agricultural and Biological Sciences | 11 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 2% |
| Other | 15 | 9% |
| Unknown | 64 | 39% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 May 2019.
All research outputs
#12,871,062
of 23,025,074 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#1,768
of 6,510 outputs
Outputs of similar age
#156,534
of 330,325 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#48
of 125 outputs
Altmetric has tracked 23,025,074 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,510 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one has gotten more attention than average, scoring higher than 71% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,325 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.
We're also able to compare this research output to 125 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.