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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection
|
|---|---|
| Published in |
Frontiers in Cellular and Infection Microbiology, February 2018
|
| DOI | 10.3389/fcimb.2018.00029 |
| Pubmed ID | |
| Authors |
Duolong Zhu, Joseph A. Sorg, Xingmin Sun |
| Abstract |
Clostridioides difficile is a Gram-positive, spore-forming, toxin-producing anaerobe, and an important nosocomial pathogen. Due to the strictly anaerobic nature of the vegetative form, spores are the main morphotype of infection and transmission of the disease. Spore formation and their subsequent germination play critical roles inC. difficileinfection (CDI) progress. Under suitable conditions,C. difficilespores will germinate and outgrow to produce the pathogenic vegetative form. During CDI,C. difficileproduces toxins (TcdA and TcdB) that are required to initiate the disease. Meanwhile, it also produces spores that are responsible for the persistence and recurrence ofC. difficilein patients. Recent studies have shed light on the regulatory mechanisms ofC. difficilesporulation and germination. This review is to summarize recent advances on the regulation of sporulation/germination inC. difficileand the corresponding therapeutic strategies that are aimed at these important processes. |
X Demographics
The data shown below were collected from the profiles of 15 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 33% |
| Mexico | 2 | 13% |
| United Kingdom | 2 | 13% |
| Italy | 1 | 7% |
| Portugal | 1 | 7% |
| Netherlands | 1 | 7% |
| Switzerland | 1 | 7% |
| Unknown | 2 | 13% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 10 | 67% |
| Members of the public | 4 | 27% |
| Practitioners (doctors, other healthcare professionals) | 1 | 7% |
Mendeley readers
The data shown below were compiled from readership statistics for 294 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 294 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 41 | 14% |
| Student > Ph. D. Student | 36 | 12% |
| Student > Master | 36 | 12% |
| Researcher | 20 | 7% |
| Student > Doctoral Student | 18 | 6% |
| Other | 25 | 9% |
| Unknown | 118 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 63 | 21% |
| Immunology and Microbiology | 28 | 10% |
| Agricultural and Biological Sciences | 23 | 8% |
| Medicine and Dentistry | 21 | 7% |
| Chemistry | 10 | 3% |
| Other | 24 | 8% |
| Unknown | 125 | 43% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 November 2022.
All research outputs
#3,003,337
of 24,294,766 outputs
Outputs from Frontiers in Cellular and Infection Microbiology
#572
of 7,375 outputs
Outputs of similar age
#68,272
of 447,093 outputs
Outputs of similar age from Frontiers in Cellular and Infection Microbiology
#15
of 124 outputs
Altmetric has tracked 24,294,766 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,375 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 447,093 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 124 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.