Title |
Systems Medicine as an Emerging Tool for Cardiovascular Genetics
|
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Published in |
Frontiers in Cardiovascular Medicine, August 2016
|
DOI | 10.3389/fcvm.2016.00027 |
Pubmed ID | |
Authors |
Tina Haase, Daniela Börnigen, Christian Müller, Tanja Zeller |
Abstract |
Cardiovascular disease (CVD) is a major contributor to morbidity and mortality worldwide. However, the pathogenesis of CVD is complex and remains elusive. Within the last years, systems medicine has emerged as a novel tool to study the complex genetic, molecular, and physiological interactions leading to diseases. In this review, we provide an overview about the current approaches for systems medicine in CVD. They include bioinformatical and experimental tools such as cell and animal models, omics technologies, network, and pathway analyses. Additionally, we discuss challenges and current literature examples where systems medicine has been successfully applied for the study of CVD. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Switzerland | 4 | 50% |
Sweden | 1 | 13% |
United States | 1 | 13% |
Unknown | 2 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 75% |
Scientists | 2 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 27 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Professor > Associate Professor | 5 | 19% |
Student > Bachelor | 4 | 15% |
Researcher | 4 | 15% |
Student > Ph. D. Student | 3 | 11% |
Other | 1 | 4% |
Other | 3 | 11% |
Unknown | 7 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 6 | 22% |
Biochemistry, Genetics and Molecular Biology | 4 | 15% |
Computer Science | 3 | 11% |
Medicine and Dentistry | 2 | 7% |
Engineering | 2 | 7% |
Other | 1 | 4% |
Unknown | 9 | 33% |