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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Effects of Serotonin in Immune Cells
|
|---|---|
| Published in |
Frontiers in Cardiovascular Medicine, July 2017
|
| DOI | 10.3389/fcvm.2017.00048 |
| Pubmed ID | |
| Authors |
Nadine Herr, Christoph Bode, Daniel Duerschmied |
| Abstract |
Serotonin [5-hydroxytryptamine (5-HT)] plays an important role in many organs as a peripheral hormone. Most of the body's serotonin is circulating in the bloodstream, transported by blood platelets and is released upon activation. The functions of serotonin are mediated by members of the 7 known mammalian serotonin receptor subtype classes (15 known subtypes), the serotonin transporter (SERT), and by covalent binding of serotonin to different effector proteins. Almost all immune cells express at least one serotonin component. In recent years, a number of immunoregulatory functions have been ascribed to serotonin. In monocytes/macrophages, for example, serotonin modulates cytokine secretion. Serotonin can also suppress the release of tumor necrosis factor-α and interleukin-1β by activating serotonin receptors. Furthermore, neutrophil recruitment and T-cell activation can both be mediated by serotonin. These are only a few of the known immunomodulatory roles of serotonin that we will review here. |
X Demographics
The data shown below were collected from the profiles of 58 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 12% |
| United Kingdom | 2 | 3% |
| Switzerland | 2 | 3% |
| Japan | 2 | 3% |
| Brazil | 2 | 3% |
| Belgium | 1 | 2% |
| France | 1 | 2% |
| India | 1 | 2% |
| Spain | 1 | 2% |
| Other | 2 | 3% |
| Unknown | 37 | 64% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 49 | 84% |
| Scientists | 6 | 10% |
| Science communicators (journalists, bloggers, editors) | 2 | 3% |
| Practitioners (doctors, other healthcare professionals) | 1 | 2% |
Mendeley readers
The data shown below were compiled from readership statistics for 459 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 459 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 62 | 14% |
| Student > Bachelor | 60 | 13% |
| Researcher | 52 | 11% |
| Student > Master | 45 | 10% |
| Student > Doctoral Student | 31 | 7% |
| Other | 65 | 14% |
| Unknown | 144 | 31% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 68 | 15% |
| Medicine and Dentistry | 55 | 12% |
| Agricultural and Biological Sciences | 36 | 8% |
| Neuroscience | 31 | 7% |
| Immunology and Microbiology | 31 | 7% |
| Other | 74 | 16% |
| Unknown | 164 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 49. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 March 2024.
All research outputs
#872,281
of 25,599,531 outputs
Outputs from Frontiers in Cardiovascular Medicine
#101
of 9,382 outputs
Outputs of similar age
#17,777
of 325,484 outputs
Outputs of similar age from Frontiers in Cardiovascular Medicine
#2
of 16 outputs
Altmetric has tracked 25,599,531 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,382 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 325,484 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.