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The Neurosteroid Allopregnanolone Modulates Specific Functions in Central and Peripheral Glial Cells

Overview of attention for article published in Frontiers in endocrinology, January 2011
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1 YouTube creator

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Title
The Neurosteroid Allopregnanolone Modulates Specific Functions in Central and Peripheral Glial Cells
Published in
Frontiers in endocrinology, January 2011
DOI 10.3389/fendo.2011.00103
Pubmed ID
Authors

Alessandro Faroni, Valerio Magnaghi

Abstract

Since the first observations on the existence of "neurosteroids" in the 1980s, our understanding of the importance of these endogenous steroids in the control of the central and peripheral nervous system (PNS) has increased progressively. Although most of the observations were made in neuronal cells, equally important are the effects that neurosteroids exert on glial cells. Among the different classes of neurosteroids acting on glial cells, the progesterone 5α-3α metabolite, allopregnanolone, displays a particular mechanism of action involving primarily the modulation of classic GABA receptors. In this review, we focus our attention on allopregnanolone because its effects on the physiology of glial cells of the central and PNS are intriguing and could potentially lead to the development of new strategies for neuroprotection and/or regeneration of injured nervous tissues.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 21%
Researcher 10 18%
Student > Bachelor 8 14%
Professor 4 7%
Student > Master 4 7%
Other 8 14%
Unknown 11 19%
Readers by discipline Count As %
Neuroscience 17 30%
Agricultural and Biological Sciences 17 30%
Medicine and Dentistry 5 9%
Veterinary Science and Veterinary Medicine 2 4%
Biochemistry, Genetics and Molecular Biology 1 2%
Other 2 4%
Unknown 13 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2023.
All research outputs
#17,302,400
of 25,394,764 outputs
Outputs from Frontiers in endocrinology
#5,293
of 13,033 outputs
Outputs of similar age
#151,890
of 190,581 outputs
Outputs of similar age from Frontiers in endocrinology
#32
of 64 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,033 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 190,581 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 64 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.