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Mechanisms and Clinical Consequences of Vascular Calcification

Overview of attention for article published in Frontiers in endocrinology, January 2012
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2 Facebook pages

Citations

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95 Dimensions

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117 Mendeley
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Title
Mechanisms and Clinical Consequences of Vascular Calcification
Published in
Frontiers in endocrinology, January 2012
DOI 10.3389/fendo.2012.00095
Pubmed ID
Authors

Dongxing Zhu, Neil C. W. Mackenzie, Colin Farquharson, Vicky E. MacRae

Abstract

Vascular calcification has severe clinical consequences and is considered an accurate predictor of future adverse cardiovascular events, including myocardial infarction and stroke. Previously vascular calcification was thought to be a passive process which involved the deposition of calcium and phosphate in arteries and cardiac valves. However, recent studies have shown that vascular calcification is a highly regulated, cell-mediated process similar to bone formation. In this article, we outline the current understanding of key mechanisms governing vascular calcification and highlight the clinical consequences. By understanding better the molecular pathways and genetic circuitry responsible for the pathological mineralization process novel drug targets may be identified and exploited to combat and reduce the detrimental effects of vascular calcification on human health.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 117 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 <1%
Unknown 116 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 21%
Student > Bachelor 15 13%
Student > Master 12 10%
Researcher 10 9%
Student > Doctoral Student 8 7%
Other 22 19%
Unknown 25 21%
Readers by discipline Count As %
Medicine and Dentistry 30 26%
Agricultural and Biological Sciences 20 17%
Biochemistry, Genetics and Molecular Biology 12 10%
Engineering 8 7%
Chemistry 5 4%
Other 14 12%
Unknown 28 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 May 2013.
All research outputs
#19,942,887
of 25,373,627 outputs
Outputs from Frontiers in endocrinology
#5,754
of 13,009 outputs
Outputs of similar age
#199,372
of 250,087 outputs
Outputs of similar age from Frontiers in endocrinology
#72
of 138 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,009 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 48th percentile – i.e., 48% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,087 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.