Title |
Somatostatinergic systems: an update on brain functions in normal and pathological aging
|
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Published in |
Frontiers in endocrinology, January 2012
|
DOI | 10.3389/fendo.2012.00154 |
Pubmed ID | |
Authors |
Guillaume Martel, Patrick Dutar, Jacques Epelbaum, Cécile Viollet |
Abstract |
Somatostatin is highly expressed in mammalian brain and is involved in many brain functions such as motor activity, sleep, sensory, and cognitive processes. Five somatostatin receptors have been described: sst(1), sst(2) (A and B), sst(3), sst(4), and sst(5), all belonging to the G-protein-coupled receptor family. During the recent years, numerous studies contributed to clarify the role of somatostatin systems, especially long-range somatostatinergic interneurons, in several functions they have been previously involved in. New advances have also been made on the alterations of somatostatinergic systems in several brain diseases and on the potential therapeutic target they represent in these pathologies. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | <1% |
Sweden | 1 | <1% |
Germany | 1 | <1% |
Peru | 1 | <1% |
Unknown | 100 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 21% |
Researcher | 20 | 19% |
Student > Master | 16 | 15% |
Student > Bachelor | 13 | 13% |
Student > Doctoral Student | 10 | 10% |
Other | 9 | 9% |
Unknown | 14 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 30 | 29% |
Neuroscience | 27 | 26% |
Medicine and Dentistry | 10 | 10% |
Biochemistry, Genetics and Molecular Biology | 8 | 8% |
Psychology | 5 | 5% |
Other | 6 | 6% |
Unknown | 18 | 17% |