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Role of PACAP in Female Fertility and Reproduction at Gonadal Level – Recent Advances

Overview of attention for article published in Frontiers in endocrinology, January 2012
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Title
Role of PACAP in Female Fertility and Reproduction at Gonadal Level – Recent Advances
Published in
Frontiers in endocrinology, January 2012
DOI 10.3389/fendo.2012.00155
Pubmed ID
Authors

Dora Reglodi, Andrea Tamas, Miklos Koppan, Donat Szogyi, Laura Welke

Abstract

Pituitary adenylate cyclase activating polypeptide (PACAP) is a pleiotropic neuropeptide, first isolated from hypothalamic extracts, but later shown in peripheral organs, such as endocrine glands, gastrointestinal system, cardiovascular system, and reproductive organs. PACAP plays a role in fertility and reproduction. Numerous studies report on the gonadal regulatory effects of PACAP at hypothalamo-hypophyseal levels. However, the local effects of PACAP at gonadal levels are also important. The present review summarizes the effects of PACAP in the ovary. PACAP and its receptors are present in the ovary, and PACAP plays a role in germ cell migration, meiotic division, follicular development, and atresia. The autocrine-paracrine hormonal effects seem to play a regulatory role in ovulation, luteinization, and follicular atrophy. Altogether, PACAP belongs to the ovarian regulatory peptides.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 13%
Student > Master 3 13%
Researcher 2 8%
Student > Postgraduate 2 8%
Professor > Associate Professor 2 8%
Other 3 13%
Unknown 9 38%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 29%
Medicine and Dentistry 2 8%
Immunology and Microbiology 2 8%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Psychology 1 4%
Other 1 4%
Unknown 10 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2012.
All research outputs
#22,963,239
of 25,604,262 outputs
Outputs from Frontiers in endocrinology
#8,475
of 13,243 outputs
Outputs of similar age
#229,454
of 251,039 outputs
Outputs of similar age from Frontiers in endocrinology
#89
of 138 outputs
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