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Receptor oligomerization: from early evidence to current understanding in class B GPCRs

Overview of attention for article published in Frontiers in endocrinology, January 2013
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Title
Receptor oligomerization: from early evidence to current understanding in class B GPCRs
Published in
Frontiers in endocrinology, January 2013
DOI 10.3389/fendo.2012.00175
Pubmed ID
Authors

Stephanie Y. L. Ng, Leo T. O. Lee, Billy K. C. Chow

Abstract

Dimerization or oligomerization of G protein-coupled receptors (GPCRs) are known to modulate receptor functions in terms of ontogeny, ligand-oriented regulation, pharmacological diversity, signal transduction, and internalization. Class B GPCRs are receptors to a family of hormones including secretin, growth hormone-releasing hormone, vasoactive intestinal polypeptide and parathyroid hormone, among others. The functional implications of receptor dimerization have extensively been studied in class A GPCRs, while less is known regarding its function in class B GPCRs. This article reviews receptor oligomerization in terms of the early evidence and current understanding particularly of class B GPCRs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
China 1 2%
Canada 1 2%
Australia 1 2%
Unknown 41 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 29%
Student > Bachelor 8 18%
Researcher 7 16%
Other 3 7%
Student > Master 3 7%
Other 5 11%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 31%
Biochemistry, Genetics and Molecular Biology 9 20%
Pharmacology, Toxicology and Pharmaceutical Science 5 11%
Chemistry 4 9%
Medicine and Dentistry 2 4%
Other 3 7%
Unknown 8 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2013.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Frontiers in endocrinology
#8,332
of 13,009 outputs
Outputs of similar age
#258,406
of 288,986 outputs
Outputs of similar age from Frontiers in endocrinology
#132
of 210 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,009 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,986 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 210 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.