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Epigenetic Control of Gonadotropin Releasing Hormone Neurons

Overview of attention for article published in Frontiers in endocrinology, January 2013
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  • Good Attention Score compared to outputs of the same age and source (68th percentile)

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Title
Epigenetic Control of Gonadotropin Releasing Hormone Neurons
Published in
Frontiers in endocrinology, January 2013
DOI 10.3389/fendo.2013.00061
Pubmed ID
Authors

Joseph R. Kurian, Ei Terasawa

Abstract

Epigenetic modifications to the genome, including DNA methylation and histone modifications, occur in response to external stimuli. Reproductive function is highly sensitive to environmental conditions including season, diet, hormonal changes, and exposure to chemical contaminants. GnRH neurons, which play a key role in reproduction, are particularly sensitive to various environmental stimuli. We recently reported that the rhesus monkey GnRH gene exhibits distinct epigenetic changes during embryonic development. More recently, we further found that a similar epigenetic phenomenon occurs across puberty. In this article we highlight recent findings, including those of afferent inputs, to describe the epigenetic control of GnRH circuit development as a link between the environment and reproductive function.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Portugal 1 2%
Unknown 39 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 22%
Student > Ph. D. Student 8 20%
Student > Bachelor 6 15%
Professor > Associate Professor 3 7%
Student > Master 3 7%
Other 8 20%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 37%
Biochemistry, Genetics and Molecular Biology 9 22%
Medicine and Dentistry 9 22%
Computer Science 2 5%
Nursing and Health Professions 1 2%
Other 2 5%
Unknown 3 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2022.
All research outputs
#15,740,207
of 25,374,917 outputs
Outputs from Frontiers in endocrinology
#3,569
of 13,012 outputs
Outputs of similar age
#177,364
of 289,004 outputs
Outputs of similar age from Frontiers in endocrinology
#64
of 210 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,012 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,004 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 210 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.