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RAGE-Mediated Inflammation, Type 2 Diabetes, and Diabetic Vascular Complication

Overview of attention for article published in Frontiers in endocrinology, January 2013
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  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

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Title
RAGE-Mediated Inflammation, Type 2 Diabetes, and Diabetic Vascular Complication
Published in
Frontiers in endocrinology, January 2013
DOI 10.3389/fendo.2013.00105
Pubmed ID
Authors

Yasuhiko Yamamoto, Hiroshi Yamamoto

Abstract

Obesity is associated with inflammation and type 2 diabetes. Innate immune system comprised of cellular and molecular components plays an important role in the inflammatory reactions. Immune cells like macrophages and their cell surface pattern-recognition receptors (PRRs) are representative for innate immunity promoting inflammatory reactions. The receptor for advanced glycation end-products (RAGE) is a member of PRRs and a proinflammatory molecular device that mediates danger signals to the body. The expression of RAGE is observed in adipocytes as well as immune cells, endothelial cells, and pancreatic β cells under certain conditions. It has been reported that RAGE is implicated in adipocyte hypertrophy and insulin resistance. RAGE-mediated regulation of adiposity and inflammation may attribute to type 2 diabetes and diabetic vascular complications.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 30 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 19%
Researcher 5 16%
Professor > Associate Professor 4 13%
Student > Bachelor 3 10%
Other 3 10%
Other 8 26%
Unknown 2 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 23%
Medicine and Dentistry 7 23%
Agricultural and Biological Sciences 7 23%
Immunology and Microbiology 2 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 2 6%
Unknown 5 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2013.
All research outputs
#14,541,657
of 25,617,409 outputs
Outputs from Frontiers in endocrinology
#2,823
of 13,243 outputs
Outputs of similar age
#165,929
of 290,242 outputs
Outputs of similar age from Frontiers in endocrinology
#56
of 210 outputs
Altmetric has tracked 25,617,409 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,243 research outputs from this source. They receive a mean Attention Score of 5.0. This one has done well, scoring higher than 77% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 290,242 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 210 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.