Title |
Regulation of Seasonal Reproduction by Hypothalamic Activation of Thyroid Hormone
|
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Published in |
Frontiers in endocrinology, January 2014
|
DOI | 10.3389/fendo.2014.00012 |
Pubmed ID | |
Authors |
Ai Shinomiya, Tsuyoshi Shimmura, Taeko Nishiwaki-Ohkawa, Takashi Yoshimura |
Abstract |
Organisms living outside the tropics measure the changes in the length of the day to adapt to seasonal changes in the environment. Animals that breed during spring and summer are called long-day breeders, while those that breed during fall are called short-day breeders. Although the influence of thyroid hormone in the regulation of seasonal reproduction has been known for several decades, its precise mechanism remained unknown. Recent studies revealed that the activation of thyroid hormone within the mediobasal hypothalamus plays a key role in this phenomenon. This localized activation of the thyroid hormone is controlled by thyrotropin (thyroid-stimulating hormone) secreted from the pars tuberalis of the pituitary gland. Although seasonal reproduction is a rate-limiting factor in animal production, genes involved in photoperiodic signal transduction pathway could emerge as potential targets to facilitate domestication. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
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Japan | 2 | 1% |
South Africa | 1 | <1% |
Unknown | 131 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 24 | 18% |
Student > Bachelor | 22 | 16% |
Student > Master | 19 | 14% |
Researcher | 14 | 10% |
Student > Doctoral Student | 8 | 6% |
Other | 15 | 11% |
Unknown | 32 | 24% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 46 | 34% |
Biochemistry, Genetics and Molecular Biology | 18 | 13% |
Neuroscience | 11 | 8% |
Veterinary Science and Veterinary Medicine | 6 | 4% |
Medicine and Dentistry | 5 | 4% |
Other | 10 | 7% |
Unknown | 38 | 28% |