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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Hypothalamic Response to the Chemo-Signal Androstadienone in Gender Dysphoric Children and Adolescents
|
|---|---|
| Published in |
Frontiers in endocrinology, May 2014
|
| DOI | 10.3389/fendo.2014.00060 |
| Pubmed ID | |
| Authors |
Sarah M. Burke, Peggy T. Cohen-Kettenis, Dick J. Veltman, Daniel T. Klink, Julie Bakker |
| Abstract |
The odorous steroid androstadienone, a putative male chemo-signal, was previously reported to evoke sex differences in hypothalamic activation in adult heterosexual men and women. In order to investigate whether puberty modulated this sex difference in response to androstadienone, we measured the hypothalamic responsiveness to this chemo-signal in 39 pre-pubertal and 41 adolescent boys and girls by means of functional magnetic resonance imaging. We then investigated whether 36 pre-pubertal children and 38 adolescents diagnosed with gender dysphoria (GD; DSM-5) exhibited sex-atypical (in accordance with their experienced gender), rather than sex-typical (in accordance with their natal sex) hypothalamic activations during olfactory stimulation with androstadienone. We found that the sex difference in responsiveness to androstadienone was already present in pre-pubertal control children and thus likely developed during early perinatal development instead of during sexual maturation. Adolescent girls and boys with GD both responded remarkably like their experienced gender, thus sex-atypical. In contrast, pre-pubertal girls with GD showed neither a typically male nor female hypothalamic activation pattern and pre-pubertal boys with GD had hypothalamic activations in response to androstadienone that were similar to control boys, thus sex-typical. We present here a unique data set of boys and girls diagnosed with GD at two different developmental stages, showing that these children possess certain sex-atypical functional brain characteristics and may have undergone atypical sexual differentiation of the brain. |
X Demographics
The data shown below were collected from the profiles of 204 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 19 | 9% |
| United Kingdom | 13 | 6% |
| Brazil | 7 | 3% |
| Canada | 6 | 3% |
| Germany | 5 | 2% |
| Netherlands | 4 | 2% |
| Australia | 3 | 1% |
| France | 3 | 1% |
| India | 2 | <1% |
| Other | 10 | 5% |
| Unknown | 132 | 65% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 191 | 94% |
| Scientists | 6 | 3% |
| Science communicators (journalists, bloggers, editors) | 4 | 2% |
| Practitioners (doctors, other healthcare professionals) | 2 | <1% |
| Unknown | 1 | <1% |
Mendeley readers
The data shown below were compiled from readership statistics for 102 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 102 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 16% |
| Student > Master | 14 | 14% |
| Student > Ph. D. Student | 11 | 11% |
| Researcher | 10 | 10% |
| Student > Doctoral Student | 7 | 7% |
| Other | 19 | 19% |
| Unknown | 25 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 25% |
| Psychology | 19 | 19% |
| Neuroscience | 13 | 13% |
| Agricultural and Biological Sciences | 9 | 9% |
| Social Sciences | 3 | 3% |
| Other | 6 | 6% |
| Unknown | 27 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 245. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2024.
All research outputs
#155,908
of 25,809,907 outputs
Outputs from Frontiers in endocrinology
#39
of 13,285 outputs
Outputs of similar age
#1,189
of 242,199 outputs
Outputs of similar age from Frontiers in endocrinology
#1
of 55 outputs
Altmetric has tracked 25,809,907 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,285 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,199 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.