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Regulation of Energy Homeostasis by GPR41

Overview of attention for article published in Frontiers in endocrinology, May 2014
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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129 Mendeley
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Title
Regulation of Energy Homeostasis by GPR41
Published in
Frontiers in endocrinology, May 2014
DOI 10.3389/fendo.2014.00081
Pubmed ID
Authors

Daisuke Inoue, Gozoh Tsujimoto, Ikuo Kimura

Abstract

Imbalances in energy regulation lead to metabolic disorders such as obesity and diabetes. Diet plays an essential role in the maintenance of body energy homeostasis by acting not only as energy source but also as a signaling modality. Excess energy increases energy expenditure, leading to a consumption of it. In addition to glucose, mammals utilize short-chain fatty acids (SCFAs), which are produced by colonic bacterial fermentation of dietary fiber, as a metabolic fuel. The roles of SCFAs in energy regulation have remained unclear, although the roles of glucose are well-studied. Recently, a G-protein-coupled receptor deorphanizing strategy successfully identified GPR41 (also called free fatty acid receptor 3 or FFAR3) as a receptor for SCFAs. GPR41 is expressed in adipose tissue, gut, and the peripheral nervous system, and it is involved in SCFA-dependent energy regulation. In this mini-review, we focus on the role of GPR41 in host energy regulation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 129 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 <1%
United Kingdom 1 <1%
United States 1 <1%
Unknown 126 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 22 17%
Student > Ph. D. Student 19 15%
Researcher 13 10%
Student > Bachelor 13 10%
Other 8 6%
Other 21 16%
Unknown 33 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 21%
Biochemistry, Genetics and Molecular Biology 21 16%
Medicine and Dentistry 17 13%
Nursing and Health Professions 7 5%
Immunology and Microbiology 5 4%
Other 17 13%
Unknown 35 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 April 2016.
All research outputs
#15,739,010
of 25,371,288 outputs
Outputs from Frontiers in endocrinology
#3,567
of 13,009 outputs
Outputs of similar age
#127,531
of 240,806 outputs
Outputs of similar age from Frontiers in endocrinology
#24
of 54 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,009 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,806 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.