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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Insulin as a Bridge between Type 2 Diabetes and Alzheimer Disease – How Anti-Diabetics Could be a Solution for Dementia
|
|---|---|
| Published in |
Frontiers in endocrinology, July 2014
|
| DOI | 10.3389/fendo.2014.00110 |
| Pubmed ID | |
| Authors |
Inês Sebastião, Emanuel Candeias, Maria S. Santos, Catarina R. de Oliveira, Paula I. Moreira, Ana I. Duarte |
| Abstract |
Type 2 diabetes (T2D) and Alzheimer disease (AD) are two major health issues nowadays. T2D is an ever increasing epidemic, affecting millions of elderly people worldwide, with major repercussions in the patients' daily life. This is mostly due to its chronic complications that may affect brain and constitutes a risk factor for AD. T2D principal hallmark is insulin resistance which also occurs in AD, rendering both pathologies more than mere unrelated diseases. This hypothesis has been reinforced in the recent years, with a high number of studies highlighting the existence of several common molecular links. As such, it is not surprising that AD has been considered as the "type 3 diabetes" or a "brain-specific T2D," supporting the idea that a beneficial therapeutic strategy against T2D might be also beneficial against AD. Herewith, we aim to review some of the recent developments on the common features between T2D and AD, namely on insulin signaling and its participation in the regulation of amyloid β (Aβ) plaque and neurofibrillary tangle formation (the two major neuropathological hallmarks of AD). We also critically analyze the promising field that some anti-T2D drugs may protect against dementia and AD, with a special emphasis on the novel incretin/glucagon-like peptide-1 receptor agonists. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 25% |
| Switzerland | 1 | 25% |
| United States | 1 | 25% |
| Unknown | 1 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 75% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Portugal | 2 | 1% |
| United States | 2 | 1% |
| United Kingdom | 2 | 1% |
| Sweden | 1 | <1% |
| Italy | 1 | <1% |
| India | 1 | <1% |
| Unknown | 175 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 33 | 18% |
| Student > Bachelor | 31 | 17% |
| Student > Master | 26 | 14% |
| Student > Ph. D. Student | 22 | 12% |
| Student > Doctoral Student | 7 | 4% |
| Other | 26 | 14% |
| Unknown | 39 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 33 | 18% |
| Agricultural and Biological Sciences | 28 | 15% |
| Neuroscience | 25 | 14% |
| Biochemistry, Genetics and Molecular Biology | 16 | 9% |
| Pharmacology, Toxicology and Pharmaceutical Science | 15 | 8% |
| Other | 23 | 13% |
| Unknown | 44 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2022.
All research outputs
#6,753,240
of 25,368,786 outputs
Outputs from Frontiers in endocrinology
#1,800
of 13,004 outputs
Outputs of similar age
#59,095
of 240,357 outputs
Outputs of similar age from Frontiers in endocrinology
#10
of 53 outputs
Altmetric has tracked 25,368,786 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 13,004 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,357 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.