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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Humanin and Age-Related Diseases: A New Link?
|
|---|---|
| Published in |
Frontiers in endocrinology, December 2014
|
| DOI | 10.3389/fendo.2014.00210 |
| Pubmed ID | |
| Authors |
Zhenwei Gong, Emir Tas, Radhika Muzumdar |
| Abstract |
Humanin (HN) is 24-amino acid mitochondria-associated peptide. Since its initial discovery over a decade ago, a role for HN has been reported in many biological processes such as apoptosis, cell survival, substrate metabolism, inflammatory response, and response to stressors such as oxidative stress, ischemia, and starvation. HN and its potent analogs have been shown to have beneficial effects in many age-related diseases including Alzheimer's disease, stroke, diabetes, myocardial ischemia and reperfusion, atherosclerosis, amyotrophic lateral sclerosis, and certain types of cancer both in vitro and in vivo. More recently, an association between HN levels, growth hormone/insulin-like growth factor-1 (GH/IGF axis), and life span was demonstrated using various mouse models with mutations in the GH/IGF axis. The goal of this review is to summarize the current understanding of the role of HN in aging and age-related diseases. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 17% |
| Switzerland | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Scientists | 1 | 17% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 116 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 116 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 17% |
| Student > Ph. D. Student | 18 | 16% |
| Student > Master | 17 | 15% |
| Student > Bachelor | 14 | 12% |
| Student > Doctoral Student | 6 | 5% |
| Other | 18 | 16% |
| Unknown | 23 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 25 | 22% |
| Biochemistry, Genetics and Molecular Biology | 20 | 17% |
| Agricultural and Biological Sciences | 12 | 10% |
| Neuroscience | 11 | 9% |
| Psychology | 3 | 3% |
| Other | 8 | 7% |
| Unknown | 37 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2020.
All research outputs
#1,911,628
of 25,374,647 outputs
Outputs from Frontiers in endocrinology
#469
of 13,012 outputs
Outputs of similar age
#25,375
of 368,046 outputs
Outputs of similar age from Frontiers in endocrinology
#2
of 63 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,012 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,046 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.