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Pheochromocytomas and Paragangliomas: Clinical and Genetic Approaches

Overview of attention for article published in Frontiers in endocrinology, August 2015
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Title
Pheochromocytomas and Paragangliomas: Clinical and Genetic Approaches
Published in
Frontiers in endocrinology, August 2015
DOI 10.3389/fendo.2015.00126
Pubmed ID
Authors

Marcia Helena Soares Costa, Tania M. Ortiga-Carvalho, Alice Dutra Violante, Mario Vaisman

Abstract

Pheochromocytomas (PCCs) and paragangliomas (PGLs) are neuroendocrine tumors derived from the chromaffin tissue. Diagnosis of these tumors is extremely important as they are linked to the hypertension syndrome with great cardiovascular morbidity and mortality. A great majority of PCCs and PGLs are sporadic and benign tumors; however, the classic idea of 10% exception of these features is changing. The description of new genes linked to familial forms of PCC/PGLs, such as succinate dehydrogenase (SDH) complex subunits, KIF1Bβ, EGLN1, TMEM127, and MAX, added to the well-known PCC familial syndrome (MEN2, VHL, and neurofibromatosis type 1) presents new challenges for diagnosis. In this review, we discuss the diversity of clinical and genetic approaches to this syndrome as well the diverse criteria that should guide genetic investigation.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Syrian Arab Republic 1 2%
Russia 1 2%
Unknown 43 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 13%
Researcher 6 13%
Student > Bachelor 5 11%
Student > Postgraduate 5 11%
Other 4 9%
Other 9 20%
Unknown 11 24%
Readers by discipline Count As %
Medicine and Dentistry 18 39%
Biochemistry, Genetics and Molecular Biology 8 17%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Mathematics 1 2%
Agricultural and Biological Sciences 1 2%
Other 1 2%
Unknown 15 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2015.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Frontiers in endocrinology
#8,334
of 13,012 outputs
Outputs of similar age
#238,041
of 277,791 outputs
Outputs of similar age from Frontiers in endocrinology
#44
of 52 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,012 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.