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X Demographics
Mendeley readers
Attention Score in Context
| Title |
GILZ as a Mediator of the Anti-Inflammatory Effects of Glucocorticoids
|
|---|---|
| Published in |
Frontiers in endocrinology, November 2015
|
| DOI | 10.3389/fendo.2015.00170 |
| Pubmed ID | |
| Authors |
Simona Ronchetti, Graziella Migliorati, Carlo Riccardi |
| Abstract |
Glucocorticoid-induced leucine zipper (GILZ) is a dexamethasone-inducible gene that mediates glucocorticoid (GC) actions in a variety of cell types, including many cells of immune system. In particular, GILZ can control T cell activities, such as activation and differentiation, mainly through its ability to homo- and hetero-dimerize with partner proteins, such as NF-κB, Ras, and C/EBP. These protein-protein interactions control the regulation of pro-inflammatory target genes. A number of in vitro and in vivo studies using mouse models of inflammatory diseases demonstrate an anti-inflammatory role for GILZ. Here, authors summarize the studies that make GILZ eligible as an anti-inflammatory protein through which GCs can act. These findings permit the future development of pharmacological tools that mimic the therapeutic effects of GCs while avoiding the detrimental ones. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 124 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 21% |
| Student > Master | 22 | 18% |
| Researcher | 17 | 14% |
| Student > Bachelor | 13 | 10% |
| Student > Doctoral Student | 7 | 6% |
| Other | 13 | 10% |
| Unknown | 26 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 32 | 26% |
| Agricultural and Biological Sciences | 21 | 17% |
| Medicine and Dentistry | 13 | 10% |
| Immunology and Microbiology | 12 | 10% |
| Neuroscience | 7 | 6% |
| Other | 10 | 8% |
| Unknown | 29 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2023.
All research outputs
#3,709,974
of 25,371,288 outputs
Outputs from Frontiers in endocrinology
#1,122
of 13,009 outputs
Outputs of similar age
#50,489
of 297,467 outputs
Outputs of similar age from Frontiers in endocrinology
#10
of 38 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,009 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 297,467 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.