↓ Skip to main content

Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone

Overview of attention for article published in Frontiers in endocrinology, July 2016
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (68th percentile)

Mentioned by

twitter
4 X users

Citations

dimensions_citation
56 Dimensions

Readers on

mendeley
97 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Bone Marrow Adipose Tissue: A New Player in Cancer Metastasis to Bone
Published in
Frontiers in endocrinology, July 2016
DOI 10.3389/fendo.2016.00090
Pubmed ID
Authors

Emma V. Morris, Claire M. Edwards

Abstract

The bone marrow is a favored site for a number of cancers, including the hematological malignancy multiple myeloma, and metastasis of breast and prostate cancer. This specialized microenvironment is highly supportive, not only for tumor growth and survival but also for the development of an associated destructive cancer-induced bone disease. The interactions between tumor cells, osteoclasts and osteoblasts are well documented. By contrast, despite occupying a significant proportion of the bone marrow, the importance of bone marrow adipose tissue is only just emerging. The ability of bone marrow adipocytes to regulate skeletal biology and hematopoiesis, combined with their metabolic activity, endocrine functions, and proximity to tumor cells means that they are ideally placed to impact both tumor growth and bone disease. This review discusses the recent advances in our understanding of how marrow adipose tissue contributes to bone metastasis and cancer-induced bone disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 97 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 19%
Student > Bachelor 14 14%
Researcher 12 12%
Student > Master 9 9%
Student > Doctoral Student 8 8%
Other 19 20%
Unknown 17 18%
Readers by discipline Count As %
Medicine and Dentistry 28 29%
Biochemistry, Genetics and Molecular Biology 21 22%
Agricultural and Biological Sciences 18 19%
Pharmacology, Toxicology and Pharmaceutical Science 4 4%
Engineering 2 2%
Other 5 5%
Unknown 19 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2016.
All research outputs
#15,169,949
of 25,374,917 outputs
Outputs from Frontiers in endocrinology
#3,365
of 13,013 outputs
Outputs of similar age
#205,882
of 371,033 outputs
Outputs of similar age from Frontiers in endocrinology
#20
of 67 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,013 research outputs from this source. They receive a mean Attention Score of 4.9. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 371,033 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.