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Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers

Overview of attention for article published in Frontiers in endocrinology, July 2016
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  • Good Attention Score compared to outputs of the same age (65th percentile)
  • Good Attention Score compared to outputs of the same age and source (78th percentile)

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2 X users
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1 Wikipedia page

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21 Mendeley
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Title
Mechanisms of Progranulin Action and Regulation in Genitourinary Cancers
Published in
Frontiers in endocrinology, July 2016
DOI 10.3389/fendo.2016.00100
Pubmed ID
Authors

Ryuta Tanimoto, Kuojung G. Lu, Shi-Qiong Xu, Simone Buraschi, Antonino Belfiore, Renato V. Iozzo, Andrea Morrione

Abstract

The growth factor progranulin has emerged in recent years as a critical regulator of transformation in several cancer models, including breast cancer, glioblastomas, leukemias, and hepatocellular carcinomas. Several laboratories, including ours, have also demonstrated an important role of progranulin in several genitourinary cancers, including ovarian, endometrial, cervical, prostate, and bladder tumors, where progranulin acts as an autocrine growth factor thereby modulating motility and invasion of transformed cells. In this review, we will focus on the mechanisms of action and regulation of progranulin signaling in genitourinary cancers with a special emphasis on prostate and bladder tumors.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 14%
Professor 3 14%
Student > Bachelor 3 14%
Student > Ph. D. Student 2 10%
Other 1 5%
Other 4 19%
Unknown 5 24%
Readers by discipline Count As %
Medicine and Dentistry 4 19%
Biochemistry, Genetics and Molecular Biology 3 14%
Neuroscience 3 14%
Nursing and Health Professions 1 5%
Unspecified 1 5%
Other 2 10%
Unknown 7 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 December 2021.
All research outputs
#7,994,598
of 25,461,852 outputs
Outputs from Frontiers in endocrinology
#2,331
of 13,105 outputs
Outputs of similar age
#126,776
of 380,111 outputs
Outputs of similar age from Frontiers in endocrinology
#14
of 65 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 13,105 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 380,111 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 78% of its contemporaries.